Esferocitose hereditária--prevalência dos défices proteicos da membrana do eritrócito.
The authors studied the relative prevalence of erythroid cytoskeletal protein defects and their relationship with the clinical course of Hereditary Spherocytosis (HS) in 39 Portuguese patients of North of Portugal (25 families). This study showed that, in the North of Portugal, HS is primarily due t...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ordem dos Médicos
2012-11-01
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| Series: | Acta Médica Portuguesa |
| Online Access: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1152 |
| _version_ | 1811195361784496128 |
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| author | Elisa Granjo Pedro Manata Noémia Torres Lurdes Rodrigues Fátima Ferreira Roswitha Bauerle Alexandre Quintanilha |
| author_facet | Elisa Granjo Pedro Manata Noémia Torres Lurdes Rodrigues Fátima Ferreira Roswitha Bauerle Alexandre Quintanilha |
| author_sort | Elisa Granjo |
| collection | DOAJ |
| description | The authors studied the relative prevalence of erythroid cytoskeletal protein defects and their relationship with the clinical course of Hereditary Spherocytosis (HS) in 39 Portuguese patients of North of Portugal (25 families). This study showed that, in the North of Portugal, HS is primarily due to anquirin deficiency (72%), followed by band 3 (20%). These findings are similar to the published data in other Caucasian populations. Anquirin primary defects have been difficult to diagnose before splenectomy, due to high reticulocytes counts. |
| first_indexed | 2024-04-12T00:42:00Z |
| format | Article |
| id | doaj.art-af02c334075c40eda3d8e76ebccac4d6 |
| institution | Directory Open Access Journal |
| issn | 0870-399X 1646-0758 |
| language | English |
| last_indexed | 2024-04-12T00:42:00Z |
| publishDate | 2012-11-01 |
| publisher | Ordem dos Médicos |
| record_format | Article |
| series | Acta Médica Portuguesa |
| spelling | doaj.art-af02c334075c40eda3d8e76ebccac4d62022-12-22T03:54:59ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07582012-11-0116210.20344/amp.1152Esferocitose hereditária--prevalência dos défices proteicos da membrana do eritrócito.Elisa Granjo0Pedro ManataNoémia TorresLurdes RodriguesFátima FerreiraRoswitha BauerleAlexandre QuintanilhaServiço de Hematologia Clínica, Hospital de S. João, Porto.The authors studied the relative prevalence of erythroid cytoskeletal protein defects and their relationship with the clinical course of Hereditary Spherocytosis (HS) in 39 Portuguese patients of North of Portugal (25 families). This study showed that, in the North of Portugal, HS is primarily due to anquirin deficiency (72%), followed by band 3 (20%). These findings are similar to the published data in other Caucasian populations. Anquirin primary defects have been difficult to diagnose before splenectomy, due to high reticulocytes counts.https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1152 |
| spellingShingle | Elisa Granjo Pedro Manata Noémia Torres Lurdes Rodrigues Fátima Ferreira Roswitha Bauerle Alexandre Quintanilha Esferocitose hereditária--prevalência dos défices proteicos da membrana do eritrócito. Acta Médica Portuguesa |
| title | Esferocitose hereditária--prevalência dos défices proteicos da membrana do eritrócito. |
| title_full | Esferocitose hereditária--prevalência dos défices proteicos da membrana do eritrócito. |
| title_fullStr | Esferocitose hereditária--prevalência dos défices proteicos da membrana do eritrócito. |
| title_full_unstemmed | Esferocitose hereditária--prevalência dos défices proteicos da membrana do eritrócito. |
| title_short | Esferocitose hereditária--prevalência dos défices proteicos da membrana do eritrócito. |
| title_sort | esferocitose hereditaria prevalencia dos defices proteicos da membrana do eritrocito |
| url | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1152 |
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