Effect of Angle Opening Parameters on Corneal Endothelial Cell Density and Intraocular Pressure after Posterior Chamber Phakic Intraocular Lens Implantation
This study aimed to investigate the time courses of angle opening parameters and the relationships of these with the corneal endothelial cell density (ECD) and the intraocular pressure (IOP) after posterior chamber phakic intraocular lens (Visian ICL<sup>TM</sup>, STAAR Surgical) implant...
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| Format: | Article |
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MDPI AG
2020-08-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/9/9/2704 |
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| author | Kazutaka Kamiya Wakako Ando Tatsuhiko Tsujisawa Masahide Takahashi Nobuyuki Shoji |
| author_facet | Kazutaka Kamiya Wakako Ando Tatsuhiko Tsujisawa Masahide Takahashi Nobuyuki Shoji |
| author_sort | Kazutaka Kamiya |
| collection | DOAJ |
| description | This study aimed to investigate the time courses of angle opening parameters and the relationships of these with the corneal endothelial cell density (ECD) and the intraocular pressure (IOP) after posterior chamber phakic intraocular lens (Visian ICL<sup>TM</sup>, STAAR Surgical) implantation. We evaluated 116 eyes of 59 consecutive patients (mean age ± standard deviation, 34.0 ± 8.8 years) who underwent V5 implantable collamer lens (ICL) implantation. Preoperatively and 1 day, 1 week, and 1, 3, and 18 months postoperatively, we quantitatively measured the angle opening distance at 500 µm (AOD500), the trabecular-iris space area (TISA500), and the trabecular iris angle (TIA500), using anterior segment optical coherence tomography (CASIA 2, Tomey), and assessed the relationships of these measurements with ECD and IOP in ICL-implanted eyes. All angle parameters (AOD500, TISA500, and TIA500) significantly decreased 1 day postoperatively but remained stable thereafter. At 18 months postoperatively, we found no significant correlations of the angle parameters with ECD (Pearson correlation coefficient <i>r</i> = −0.108, <i>p</i> = 0.249 for AOD500; <i>r</i> = −0.162, <i>p</i> = 0.083 for TISA500; <i>r</i> = −0.022, <i>p</i> = 0.815 for TIA500) or between the angle parameters and IOP (<i>r</i> = −0.106, <i>p</i> = 0.256 for AOD500; <i>r</i> = −0.021, <i>p</i> = 0.826 for TISA500; <i>r</i> = −0.018, <i>p</i> = 0.850 for TIA500). The angle opening metrics significantly decreased immediately after ICL implantation but remained stable thereafter. Narrowing of the angle did not significantly affect ECD or IOP in ICL-implanted eyes during the 18-month postoperative period. |
| first_indexed | 2024-03-10T17:03:08Z |
| format | Article |
| id | doaj.art-af0363b3db0d4639b518ffd56d2567ff |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T17:03:08Z |
| publishDate | 2020-08-01 |
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| series | Journal of Clinical Medicine |
| spelling | doaj.art-af0363b3db0d4639b518ffd56d2567ff2023-11-20T10:54:19ZengMDPI AGJournal of Clinical Medicine2077-03832020-08-0199270410.3390/jcm9092704Effect of Angle Opening Parameters on Corneal Endothelial Cell Density and Intraocular Pressure after Posterior Chamber Phakic Intraocular Lens ImplantationKazutaka Kamiya0Wakako Ando1Tatsuhiko Tsujisawa2Masahide Takahashi3Nobuyuki Shoji4Visual Physiology, School of Allied Health Sciences, Kitasato University, Kanagawa 252-0373, JapanDepartment of Ophthalmology, School of Medicine, Kitasato University, Kanagawa 252-0374, JapanDepartment of Ophthalmology, School of Medicine, Kitasato University, Kanagawa 252-0374, JapanDepartment of Ophthalmology, School of Medicine, Kitasato University, Kanagawa 252-0374, JapanDepartment of Ophthalmology, School of Medicine, Kitasato University, Kanagawa 252-0374, JapanThis study aimed to investigate the time courses of angle opening parameters and the relationships of these with the corneal endothelial cell density (ECD) and the intraocular pressure (IOP) after posterior chamber phakic intraocular lens (Visian ICL<sup>TM</sup>, STAAR Surgical) implantation. We evaluated 116 eyes of 59 consecutive patients (mean age ± standard deviation, 34.0 ± 8.8 years) who underwent V5 implantable collamer lens (ICL) implantation. Preoperatively and 1 day, 1 week, and 1, 3, and 18 months postoperatively, we quantitatively measured the angle opening distance at 500 µm (AOD500), the trabecular-iris space area (TISA500), and the trabecular iris angle (TIA500), using anterior segment optical coherence tomography (CASIA 2, Tomey), and assessed the relationships of these measurements with ECD and IOP in ICL-implanted eyes. All angle parameters (AOD500, TISA500, and TIA500) significantly decreased 1 day postoperatively but remained stable thereafter. At 18 months postoperatively, we found no significant correlations of the angle parameters with ECD (Pearson correlation coefficient <i>r</i> = −0.108, <i>p</i> = 0.249 for AOD500; <i>r</i> = −0.162, <i>p</i> = 0.083 for TISA500; <i>r</i> = −0.022, <i>p</i> = 0.815 for TIA500) or between the angle parameters and IOP (<i>r</i> = −0.106, <i>p</i> = 0.256 for AOD500; <i>r</i> = −0.021, <i>p</i> = 0.826 for TISA500; <i>r</i> = −0.018, <i>p</i> = 0.850 for TIA500). The angle opening metrics significantly decreased immediately after ICL implantation but remained stable thereafter. Narrowing of the angle did not significantly affect ECD or IOP in ICL-implanted eyes during the 18-month postoperative period.https://www.mdpi.com/2077-0383/9/9/2704angle open distancehole ICLendothelial cell densityintraocular pressureICLphakic IOL |
| spellingShingle | Kazutaka Kamiya Wakako Ando Tatsuhiko Tsujisawa Masahide Takahashi Nobuyuki Shoji Effect of Angle Opening Parameters on Corneal Endothelial Cell Density and Intraocular Pressure after Posterior Chamber Phakic Intraocular Lens Implantation Journal of Clinical Medicine angle open distance hole ICL endothelial cell density intraocular pressure ICL phakic IOL |
| title | Effect of Angle Opening Parameters on Corneal Endothelial Cell Density and Intraocular Pressure after Posterior Chamber Phakic Intraocular Lens Implantation |
| title_full | Effect of Angle Opening Parameters on Corneal Endothelial Cell Density and Intraocular Pressure after Posterior Chamber Phakic Intraocular Lens Implantation |
| title_fullStr | Effect of Angle Opening Parameters on Corneal Endothelial Cell Density and Intraocular Pressure after Posterior Chamber Phakic Intraocular Lens Implantation |
| title_full_unstemmed | Effect of Angle Opening Parameters on Corneal Endothelial Cell Density and Intraocular Pressure after Posterior Chamber Phakic Intraocular Lens Implantation |
| title_short | Effect of Angle Opening Parameters on Corneal Endothelial Cell Density and Intraocular Pressure after Posterior Chamber Phakic Intraocular Lens Implantation |
| title_sort | effect of angle opening parameters on corneal endothelial cell density and intraocular pressure after posterior chamber phakic intraocular lens implantation |
| topic | angle open distance hole ICL endothelial cell density intraocular pressure ICL phakic IOL |
| url | https://www.mdpi.com/2077-0383/9/9/2704 |
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