Modulation of Viral Programmed Ribosomal Frameshifting and Stop Codon Readthrough by the Host Restriction Factor Shiftless

The product of the interferon-stimulated gene <i>C19orf66</i>, Shiftless (SHFL)<i>,</i> restricts human immunodeficiency virus replication through downregulation of the efficiency of the viral <i>gag/pol</i> frameshifting signal. In this study, we demonstrate that...

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Bibliographic Details
Main Authors: Sawsan Napthine, Chris H. Hill, Holly C. M. Nugent, Ian Brierley
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/7/1230