Modulation of Viral Programmed Ribosomal Frameshifting and Stop Codon Readthrough by the Host Restriction Factor Shiftless

Modulation of Viral Programmed Ribosomal Frameshifting and Stop Codon Readthrough by the Host Restriction Factor Shiftless

The product of the interferon-stimulated gene <i>C19orf66</i>, Shiftless (SHFL)<i>,</i> restricts human immunodeficiency virus replication through downregulation of the efficiency of the viral <i>gag/pol</i> frameshifting signal. In this study, we demonstrate that...

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Bibliographic Details
Main Authors: Sawsan Napthine, Chris H. Hill, Holly C. M. Nugent, Ian Brierley
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Viruses
Subjects:
ribosome
frameshift
readthrough
Shiftless
virus
Online Access:https://www.mdpi.com/1999-4915/13/7/1230

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