Myeloid-Derived Suppressor Cells in Kidney Transplant Recipients and the Effect of Maintenance Immunotherapy

Myeloid-Derived Suppressor Cells in Kidney Transplant Recipients and the Effect of Maintenance Immunotherapy

Myeloid-derived suppressor cells (MDSC) represent a heterogeneous group of myeloid regulatory cells that were originally described in cancer. Several studies in animal models point to MDSC as important players in the induction of allograft tolerance due to their immune modulatory function. Most of t...

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Bibliographic Details
Main Authors:	María Iglesias-Escudero, David Sansegundo-Arribas, Paloma Riquelme, David Merino-Fernández, Sandra Guiral-Foz, Carmen Pérez, Rosalia Valero, Juan Carlos Ruiz, Emilio Rodrigo, Patricia Lamadrid-Perojo, James A. Hutchinson, Jordi Ochando, Marcos López-Hoyos
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-04-01
Series:	Frontiers in Immunology
Subjects:	kidney transplantation mTOR inhibition myeloid-derived suppressor cells tacrolimus immunosuppression
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2020.00643/full

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