Unmasking of intracranial metastatic melanoma during ipilimumab/nivolumab therapy: case report and literature review

Unmasking of intracranial metastatic melanoma during ipilimumab/nivolumab therapy: case report and literature review

Abstract Background While data from several studies over the last decade has demonstrated that introduction of immunologic checkpoint blockage therapy with anti-CTLA-4/PD-1 drugs leads to improved survival in metastatic melanoma patients, relatively little is known about brain-specific therapeutic r...

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Bibliographic Details
Main Authors: Marin A. McDonald, Parag Sanghvi, Julie Bykowski, Gregory A. Daniels
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cancer
Subjects:
Immunotherapy
Checkpoint blockade
Metastatic melanoma
Intracranial metastases
Online Access:http://link.springer.com/article/10.1186/s12885-018-4470-y

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