Characterization, Antimicrobial and Anticancer Properties of Palladium Nanoparticles Biosynthesized Optimally Using Saudi Propolis
Due to their unique physicochemical characteristics, palladium nanoparticles (Pd-NPs) have shown tremendous promise in biological applications. The biosynthesis of Pd-NPs employing Saudi propolis has been designed to be environmental, fast, controlled, and cost-effective. The formation and stability...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-10-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/11/10/2666 |
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| author | Maged S. Al-Fakeh Samir Osman Mohammed Osman Malek Gassoumi Mokded Rabhi Mohamed Omer |
| author_facet | Maged S. Al-Fakeh Samir Osman Mohammed Osman Malek Gassoumi Mokded Rabhi Mohamed Omer |
| author_sort | Maged S. Al-Fakeh |
| collection | DOAJ |
| description | Due to their unique physicochemical characteristics, palladium nanoparticles (Pd-NPs) have shown tremendous promise in biological applications. The biosynthesis of Pd-NPs employing Saudi propolis has been designed to be environmental, fast, controlled, and cost-effective. The formation and stability of biosynthesized Pd-NPs by Saudi propolis extract were proved by ultraviolet–visible spectrophotometry (UV-Vis), Fourier-transform infrared spectroscopy (FT-IR), and Zeta potential analysis. Transmission electron microscopy (TEM), scanning electron microscopy (SEM), and X-ray diffraction (XRD) findings show that the average particle size of Pd-NPs is between 3.14 and 4.62 nm, which is in quantum scale. The Saudi propolis enhanced the antimicrobial activity against <i>B. subtilis</i>, <i>S. aureus</i>, <i>E. coli</i>, <i>K. pneumoniae</i>, and <i>C. albicans</i>. Pd-NPs show effective anticancer activity against ductal carcinoma (MCF-7) with IC50 of 104.79 µg/mL. |
| first_indexed | 2024-03-10T06:19:27Z |
| format | Article |
| id | doaj.art-af0a609669d148af92ad2face3742b85 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-10T06:19:27Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-af0a609669d148af92ad2face3742b852023-11-22T19:24:49ZengMDPI AGNanomaterials2079-49912021-10-011110266610.3390/nano11102666Characterization, Antimicrobial and Anticancer Properties of Palladium Nanoparticles Biosynthesized Optimally Using Saudi PropolisMaged S. Al-Fakeh0Samir Osman Mohammed Osman1Malek Gassoumi2Mokded Rabhi3Mohamed Omer4Department of Chemistry, College of Science, Qassim University, Buraidah 51452, Saudi ArabiaDepartment of Physics, College of Science, Ibb University, Ibb 009674, YemenDepartment of Physics, College of Science, Qassim University, P.O. 64, Buraidah 51452, Saudi ArabiaDepartment of Plant Production and Protection, College of Agriculture and Veterinary Medicine, Qassim University, Qassim 51452, Saudi ArabiaDepartment of Radiologic Science, College of Applied Medical Sciences, Buraidah 51452, Saudi ArabiaDue to their unique physicochemical characteristics, palladium nanoparticles (Pd-NPs) have shown tremendous promise in biological applications. The biosynthesis of Pd-NPs employing Saudi propolis has been designed to be environmental, fast, controlled, and cost-effective. The formation and stability of biosynthesized Pd-NPs by Saudi propolis extract were proved by ultraviolet–visible spectrophotometry (UV-Vis), Fourier-transform infrared spectroscopy (FT-IR), and Zeta potential analysis. Transmission electron microscopy (TEM), scanning electron microscopy (SEM), and X-ray diffraction (XRD) findings show that the average particle size of Pd-NPs is between 3.14 and 4.62 nm, which is in quantum scale. The Saudi propolis enhanced the antimicrobial activity against <i>B. subtilis</i>, <i>S. aureus</i>, <i>E. coli</i>, <i>K. pneumoniae</i>, and <i>C. albicans</i>. Pd-NPs show effective anticancer activity against ductal carcinoma (MCF-7) with IC50 of 104.79 µg/mL.https://www.mdpi.com/2079-4991/11/10/2666Pd-NPsantimicrobialanticancer |
| spellingShingle | Maged S. Al-Fakeh Samir Osman Mohammed Osman Malek Gassoumi Mokded Rabhi Mohamed Omer Characterization, Antimicrobial and Anticancer Properties of Palladium Nanoparticles Biosynthesized Optimally Using Saudi Propolis Nanomaterials Pd-NPs antimicrobial anticancer |
| title | Characterization, Antimicrobial and Anticancer Properties of Palladium Nanoparticles Biosynthesized Optimally Using Saudi Propolis |
| title_full | Characterization, Antimicrobial and Anticancer Properties of Palladium Nanoparticles Biosynthesized Optimally Using Saudi Propolis |
| title_fullStr | Characterization, Antimicrobial and Anticancer Properties of Palladium Nanoparticles Biosynthesized Optimally Using Saudi Propolis |
| title_full_unstemmed | Characterization, Antimicrobial and Anticancer Properties of Palladium Nanoparticles Biosynthesized Optimally Using Saudi Propolis |
| title_short | Characterization, Antimicrobial and Anticancer Properties of Palladium Nanoparticles Biosynthesized Optimally Using Saudi Propolis |
| title_sort | characterization antimicrobial and anticancer properties of palladium nanoparticles biosynthesized optimally using saudi propolis |
| topic | Pd-NPs antimicrobial anticancer |
| url | https://www.mdpi.com/2079-4991/11/10/2666 |
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