The Accuracy of Near Infrared Autofluorescence in Identifying Parathyroid Gland During Thyroid and Parathyroid Surgery: A Meta-Analysis
ObjectiveWe aim to assess the accuracy of near infrared autofluorescence in identifying parathyroid gland during thyroid and parathyroid surgery.MethodA systematic literature search was conducted by using PubMed, Embase, and the Cochrane Library electronic databases for studies that were published u...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-06-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2021.701253/full |
| _version_ | 1819102263351705600 |
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| author | Bin Wang Chun-Rong Zhu Hong Liu Xin-Min Yao Jian Wu |
| author_facet | Bin Wang Chun-Rong Zhu Hong Liu Xin-Min Yao Jian Wu |
| author_sort | Bin Wang |
| collection | DOAJ |
| description | ObjectiveWe aim to assess the accuracy of near infrared autofluorescence in identifying parathyroid gland during thyroid and parathyroid surgery.MethodA systematic literature search was conducted by using PubMed, Embase, and the Cochrane Library electronic databases for studies that were published up to February 2021. The reference lists of the retrieved articles were also reviewed. Two authors independently assessed the methodological quality and extracted the data. A random-effects model was used to calculate the combined variable. Publication bias in these studies was evaluated with the Deeks’ funnel plots.ResultA total of 24 studies involving 2,062 patients and 6,680 specimens were included for the meta-analysis. The overall combined sensitivity and specificity, and the area under curve of near infrared autofluorescence were 0.96, 0.96, and 0.99, respectively. Significant heterogeneities were presented (Sen: I2 = 87.97%, Spe: I2 = 65.38%). In the subgroup of thyroid surgery, the combined sensitivity and specificity, and the area under curve of near infrared autofluorescence was 0.98, 0.99, and 0.99, respectively, and the heterogeneities were moderate (Sen: I2 = 59.71%, Spe: I2 = 67.65%).ConclusionNear infrared autofluorescence is an excellent indicator for identifying parathyroid gland during thyroid and parathyroid surgery. |
| first_indexed | 2024-12-22T01:31:47Z |
| format | Article |
| id | doaj.art-af0a9bbfb13b40e6b5a2a60fc9bb40a1 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-12-22T01:31:47Z |
| publishDate | 2021-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-af0a9bbfb13b40e6b5a2a60fc9bb40a12022-12-21T18:43:29ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922021-06-011210.3389/fendo.2021.701253701253The Accuracy of Near Infrared Autofluorescence in Identifying Parathyroid Gland During Thyroid and Parathyroid Surgery: A Meta-AnalysisBin Wang0Chun-Rong Zhu1Hong Liu2Xin-Min Yao3Jian Wu4Department of Thyroid and Breast Surgery, Chengdu Third People’s Hospital, Chengdu, ChinaDepartment of Chemistry, School of Basic Medical Science, North Sichuan Medical College, Nanchong, ChinaDepartment of Thyroid and Breast Surgery, Chengdu Third People’s Hospital, Chengdu, ChinaDepartment of Thyroid and Breast Surgery, Chengdu Third People’s Hospital, Chengdu, ChinaDepartment of Thyroid and Breast Surgery, Chengdu Third People’s Hospital, Chengdu, ChinaObjectiveWe aim to assess the accuracy of near infrared autofluorescence in identifying parathyroid gland during thyroid and parathyroid surgery.MethodA systematic literature search was conducted by using PubMed, Embase, and the Cochrane Library electronic databases for studies that were published up to February 2021. The reference lists of the retrieved articles were also reviewed. Two authors independently assessed the methodological quality and extracted the data. A random-effects model was used to calculate the combined variable. Publication bias in these studies was evaluated with the Deeks’ funnel plots.ResultA total of 24 studies involving 2,062 patients and 6,680 specimens were included for the meta-analysis. The overall combined sensitivity and specificity, and the area under curve of near infrared autofluorescence were 0.96, 0.96, and 0.99, respectively. Significant heterogeneities were presented (Sen: I2 = 87.97%, Spe: I2 = 65.38%). In the subgroup of thyroid surgery, the combined sensitivity and specificity, and the area under curve of near infrared autofluorescence was 0.98, 0.99, and 0.99, respectively, and the heterogeneities were moderate (Sen: I2 = 59.71%, Spe: I2 = 67.65%).ConclusionNear infrared autofluorescence is an excellent indicator for identifying parathyroid gland during thyroid and parathyroid surgery.https://www.frontiersin.org/articles/10.3389/fendo.2021.701253/fullnear infraredautofluorescenceparathyroid glandsurgerymeta-analysis |
| spellingShingle | Bin Wang Chun-Rong Zhu Hong Liu Xin-Min Yao Jian Wu The Accuracy of Near Infrared Autofluorescence in Identifying Parathyroid Gland During Thyroid and Parathyroid Surgery: A Meta-Analysis Frontiers in Endocrinology near infrared autofluorescence parathyroid gland surgery meta-analysis |
| title | The Accuracy of Near Infrared Autofluorescence in Identifying Parathyroid Gland During Thyroid and Parathyroid Surgery: A Meta-Analysis |
| title_full | The Accuracy of Near Infrared Autofluorescence in Identifying Parathyroid Gland During Thyroid and Parathyroid Surgery: A Meta-Analysis |
| title_fullStr | The Accuracy of Near Infrared Autofluorescence in Identifying Parathyroid Gland During Thyroid and Parathyroid Surgery: A Meta-Analysis |
| title_full_unstemmed | The Accuracy of Near Infrared Autofluorescence in Identifying Parathyroid Gland During Thyroid and Parathyroid Surgery: A Meta-Analysis |
| title_short | The Accuracy of Near Infrared Autofluorescence in Identifying Parathyroid Gland During Thyroid and Parathyroid Surgery: A Meta-Analysis |
| title_sort | accuracy of near infrared autofluorescence in identifying parathyroid gland during thyroid and parathyroid surgery a meta analysis |
| topic | near infrared autofluorescence parathyroid gland surgery meta-analysis |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2021.701253/full |
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