Amyloidosis in Behcet′s disease
Behcet′s disease (BD) is a multisystem vasculitis with protean manifestations. It is characterized by a heightened state of inflammation, although the factors that initiate and sustain this inflammation are not clear. We report some cases of BD-associated amyloidosis and have similar features. The p...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Saudi Journal of Kidney Diseases and Transplantation |
| Online Access: | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2015;volume=26;issue=1;spage=132;epage=134;aulast=Ghorbel |
| _version_ | 1811257711259549696 |
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| author | I Ben Ghorbel N Bel Feki T Ben Salem M Lamloum M H Houman |
| author_facet | I Ben Ghorbel N Bel Feki T Ben Salem M Lamloum M H Houman |
| author_sort | I Ben Ghorbel |
| collection | DOAJ |
| description | Behcet′s disease (BD) is a multisystem vasculitis with protean manifestations. It is characterized by a heightened state of inflammation, although the factors that initiate and sustain this inflammation are not clear. We report some cases of BD-associated amyloidosis and have similar features. The patients developed nephrotic syndrome due to secondary amyloidosis, which was refractory to the immunosuppressive agents. Two patients expired and the third was lost to follow-up during the course. The BD complicated with amyloidosis is associated with high mortality despite the current aggressive therapy. |
| first_indexed | 2024-04-12T18:01:43Z |
| format | Article |
| id | doaj.art-af0b00f9c3d946e08f790978745c5360 |
| institution | Directory Open Access Journal |
| issn | 1319-2442 |
| language | English |
| last_indexed | 2024-04-12T18:01:43Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Kidney Diseases and Transplantation |
| spelling | doaj.art-af0b00f9c3d946e08f790978745c53602022-12-22T03:22:08ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422015-01-0126113213410.4103/1319-2442.148761Amyloidosis in Behcet′s diseaseI Ben GhorbelN Bel FekiT Ben SalemM LamloumM H HoumanBehcet′s disease (BD) is a multisystem vasculitis with protean manifestations. It is characterized by a heightened state of inflammation, although the factors that initiate and sustain this inflammation are not clear. We report some cases of BD-associated amyloidosis and have similar features. The patients developed nephrotic syndrome due to secondary amyloidosis, which was refractory to the immunosuppressive agents. Two patients expired and the third was lost to follow-up during the course. The BD complicated with amyloidosis is associated with high mortality despite the current aggressive therapy.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2015;volume=26;issue=1;spage=132;epage=134;aulast=Ghorbel |
| spellingShingle | I Ben Ghorbel N Bel Feki T Ben Salem M Lamloum M H Houman Amyloidosis in Behcet′s disease Saudi Journal of Kidney Diseases and Transplantation |
| title | Amyloidosis in Behcet′s disease |
| title_full | Amyloidosis in Behcet′s disease |
| title_fullStr | Amyloidosis in Behcet′s disease |
| title_full_unstemmed | Amyloidosis in Behcet′s disease |
| title_short | Amyloidosis in Behcet′s disease |
| title_sort | amyloidosis in behcet s disease |
| url | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2015;volume=26;issue=1;spage=132;epage=134;aulast=Ghorbel |
| work_keys_str_mv | AT ibenghorbel amyloidosisinbehcetsdisease AT nbelfeki amyloidosisinbehcetsdisease AT tbensalem amyloidosisinbehcetsdisease AT mlamloum amyloidosisinbehcetsdisease AT mhhouman amyloidosisinbehcetsdisease |