A promoter SNP rs4073T>A in the common allele of the interleukin 8 gene is associated with the development of idiopathic pulmonary fibrosis via the IL-8 protein enhancing mode

A promoter SNP rs4073T>A in the common allele of the interleukin 8 gene is associated with the development of idiopathic pulmonary fibrosis via the IL-8 protein enhancing mode

<p>Abstract</p> <p>Background</p> <p>Interleukin-8 (IL-8) is a potent chemo-attractant cytokine responsible for neutrophil infiltration in lungs with idiopathic pulmonary fibrosis (IPF). The IL-8 protein and mRNA expression are increased in the lung with IPF. We evaluat...

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Main Authors: Chung Man, Park In, Choi Byoung, Park Jeong, Jeong Sung, Lee Kye, Jung Ki-Suck, Han Sung, Kim Young, Kim Yang-Ki, Uh Soo-Taek, Shin Hwa-Kyun, Park Jai-Soung, Jang An-Soo, Kim Do-Jin, Park Jong-Sook, Park Sung-Woo, Lee Shin-Hwa, Park Byung-Lae, Ahn Mi-Hyun, Shin Hyoung, Song Jin, Kim Dong, Park Choon-Sik, Shim Young-Soo
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/12/1/73

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