Nonalcoholic fatty liver disease – an etiological approach

Nonalcoholic fatty liver disease (NAFLD) is defined as the presence of fat in the liver (hepatic steatosis) either on imaging or on liver histology only after the exclusion of secondary causes of fat accumulation in the liver (e.g. high alcohol drinking, drugs and other medical ailments). Conside...

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Bibliographic Details
Main Authors: Florentina Ioniță Radu, Mariana Jinga, Petruț Nuță, Raluca S. Costache, Săndica Bucurică, Bogdan Macadon, Vasile Balaban, Mihăiță Pătrășescu
Format: Article
Language:English
Published: Carol Davila University of Medicine and Pharmacy Publishing House 2014-06-01
Series:Romanian Journal of Military Medicine
Online Access:http://revistamedicinamilitara.ro/wp-content/uploads/2016/04/2014-12-full.35-41.pdf
Description
Summary:Nonalcoholic fatty liver disease (NAFLD) is defined as the presence of fat in the liver (hepatic steatosis) either on imaging or on liver histology only after the exclusion of secondary causes of fat accumulation in the liver (e.g. high alcohol drinking, drugs and other medical ailments). Considering the fact that there are many causes of hepatic steatosis, the term NAFLD is reserved for the liver disease that is predominantly associated with obesity and metabolic syndrome. The presence of inflammation and cell injury defines steatohepatitis (NASH) which has the potential to evolve into cirrhosis and hepatocarcinoma, being, therefore, the stage of NAFLD most amenable to treatment. Among the treatments available, the most important are: weight loss, vitamin E and, last but not least, probiotics.
ISSN:1222-5126
2501-2312