The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans
Abstract Background Central skull-base osteomyelitis (CSBO) represents a life-threatening complication of external ear canal infection. Computed tomography (CT) and magnetic resonance imaging (MRI) play key roles in assessment of CSBO progression. Methods Twelve patients with CSBO were included in a...
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| Format: | Article |
| Language: | English |
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BMC
2019-08-01
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| Series: | BMC Medical Imaging |
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| Online Access: | http://link.springer.com/article/10.1186/s12880-019-0331-7 |
| _version_ | 1811288013364264960 |
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| author | J. Mejzlik M. Cerny L. Zeinerova J. Dedkova J. Kopriva K. Zadrobilek J. Adamkov V. Chrobok V. Pellantova |
| author_facet | J. Mejzlik M. Cerny L. Zeinerova J. Dedkova J. Kopriva K. Zadrobilek J. Adamkov V. Chrobok V. Pellantova |
| author_sort | J. Mejzlik |
| collection | DOAJ |
| description | Abstract Background Central skull-base osteomyelitis (CSBO) represents a life-threatening complication of external ear canal infection. Computed tomography (CT) and magnetic resonance imaging (MRI) play key roles in assessment of CSBO progression. Methods Twelve patients with CSBO were included in a retrospective clinical study. In total, 62 scans (30 CTs and 32 MRIs) were performed to evaluate the extent of inflammatory changes. The scans were read independently by two radiologists specialised in imaging of the head and neck. The regions under the skull base were specified using the online Anatomy Atlas of the skull base. To clarify the timeline, the time period was divided into four parts, and inflammatory changes in the skull-base regions were tracked. Data were statistically analysed. Results In early stages of the disease, CT scan detects inflammatory changes closely related to the stylomastoid foramen and medially to the posterior belly of the digastric muscle, changes which have been proved to be crucial for the diagnosis of CSBO. Later the infection spreads to the contralateral side causing demineralisation of the bones. Conclusion Imaging methods play a crucial role not only in establishing the diagnosis, but also in anticipating the direction of infection spread underneath the skull base. |
| first_indexed | 2024-04-13T03:28:37Z |
| format | Article |
| id | doaj.art-af0fc7f69e2e4df68ee737addcbf766d |
| institution | Directory Open Access Journal |
| issn | 1471-2342 |
| language | English |
| last_indexed | 2024-04-13T03:28:37Z |
| publishDate | 2019-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medical Imaging |
| spelling | doaj.art-af0fc7f69e2e4df68ee737addcbf766d2022-12-22T03:04:34ZengBMCBMC Medical Imaging1471-23422019-08-0119111110.1186/s12880-019-0331-7The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scansJ. Mejzlik0M. Cerny1L. Zeinerova2J. Dedkova3J. Kopriva4K. Zadrobilek5J. Adamkov6V. Chrobok7V. Pellantova8Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Charles University in PragueDepartment of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Charles University in PragueDepartment of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Charles University in PragueDepartment of Radiology, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Charles University in PragueDepartment of Radiology, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Charles University in PragueDepartment of Neurosurgery, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Charles University in PragueDepartment of Neurosurgery, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Charles University in PragueDepartment of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Charles University in PragueDepartment of Infectious Diseases, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Charles University in PragueAbstract Background Central skull-base osteomyelitis (CSBO) represents a life-threatening complication of external ear canal infection. Computed tomography (CT) and magnetic resonance imaging (MRI) play key roles in assessment of CSBO progression. Methods Twelve patients with CSBO were included in a retrospective clinical study. In total, 62 scans (30 CTs and 32 MRIs) were performed to evaluate the extent of inflammatory changes. The scans were read independently by two radiologists specialised in imaging of the head and neck. The regions under the skull base were specified using the online Anatomy Atlas of the skull base. To clarify the timeline, the time period was divided into four parts, and inflammatory changes in the skull-base regions were tracked. Data were statistically analysed. Results In early stages of the disease, CT scan detects inflammatory changes closely related to the stylomastoid foramen and medially to the posterior belly of the digastric muscle, changes which have been proved to be crucial for the diagnosis of CSBO. Later the infection spreads to the contralateral side causing demineralisation of the bones. Conclusion Imaging methods play a crucial role not only in establishing the diagnosis, but also in anticipating the direction of infection spread underneath the skull base.http://link.springer.com/article/10.1186/s12880-019-0331-7Central skull-base osteomyelitisImagingTreatmentCranial nerve palsy, computed tomography |
| spellingShingle | J. Mejzlik M. Cerny L. Zeinerova J. Dedkova J. Kopriva K. Zadrobilek J. Adamkov V. Chrobok V. Pellantova The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans BMC Medical Imaging Central skull-base osteomyelitis Imaging Treatment Cranial nerve palsy, computed tomography |
| title | The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans |
| title_full | The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans |
| title_fullStr | The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans |
| title_full_unstemmed | The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans |
| title_short | The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans |
| title_sort | routes of infection spread in central skull base osteomyelitis and the diagnostic role of ct and mri scans |
| topic | Central skull-base osteomyelitis Imaging Treatment Cranial nerve palsy, computed tomography |
| url | http://link.springer.com/article/10.1186/s12880-019-0331-7 |
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