Lipid Profile and Antihypertensive Drugs
Background: Hypertension and dyslipidemia are cardiovascular risk factors that commonly coexist . Objective : To evaluate the effects of ß - blocker (Atenolol) , ACE inhibitor (Captopril) calcium Channel blocker (Nefidipin ) and diuretics on serum lipid profiles . Method: Thirty untreated hypertens...
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| Format: | Article |
| Language: | English |
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University of Baghdad/ Al-Kindy College of Medicine
2009-06-01
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| Series: | مجله كليه طب الكندي |
| Subjects: | |
| Online Access: | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/713 |
| _version_ | 1828112358411599872 |
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| author | Abdul-Khader A. Abdul-Khader |
| author_facet | Abdul-Khader A. Abdul-Khader |
| author_sort | Abdul-Khader A. Abdul-Khader |
| collection | DOAJ |
| description |
Background: Hypertension and dyslipidemia are
cardiovascular risk factors that commonly coexist .
Objective : To evaluate the effects of ß - blocker
(Atenolol) , ACE inhibitor (Captopril) calcium Channel
blocker (Nefidipin ) and diuretics on serum lipid profiles .
Method: Thirty untreated hypertensive and 147
hypertensive patient treated with these antihypertensive
drugs, attending different public health clinics in Basrah
pronivce were enrolled in this study .
Serum lipid profile were determined enzymaticaly using kits
from BioMerieux, France .
Result : The study has revealed that ß-blocker do not
significantly affect total cholesterol ( TC ) and LDLcholesterol , but increase significantly triglyceride (TG) and
VLDL – cholesterol and decrease HDL – cholesterol.
Diuretics causes a significant elevation of TG with generally
no significant changes in TC , LDL – cholesterol , VLDL –
cholesterol and HDL-cholesterol. ACE inhibitor and calcium
channel blockers appears to have no significant effect on
plasma lipids .
Conclusion :It may important to measure blood lipid levels
to identify pre-existing hyperlipidemia before starting the
antihypertensive therapy and to select antihypertensive agent
that will not influence the lipid profile or interfere with the
therapy of hyperlipidemi
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| first_indexed | 2024-04-11T11:47:54Z |
| format | Article |
| id | doaj.art-af10857c151d4f6c8a65817650a1069a |
| institution | Directory Open Access Journal |
| issn | 1810-9543 2521-4365 |
| language | English |
| last_indexed | 2024-04-11T11:47:54Z |
| publishDate | 2009-06-01 |
| publisher | University of Baghdad/ Al-Kindy College of Medicine |
| record_format | Article |
| series | مجله كليه طب الكندي |
| spelling | doaj.art-af10857c151d4f6c8a65817650a1069a2022-12-22T04:25:28ZengUniversity of Baghdad/ Al-Kindy College of Medicineمجله كليه طب الكندي1810-95432521-43652009-06-0151Lipid Profile and Antihypertensive DrugsAbdul-Khader A. Abdul-Khader0Department of Biochemistry, College of Medicine , University of Basrah Background: Hypertension and dyslipidemia are cardiovascular risk factors that commonly coexist . Objective : To evaluate the effects of ß - blocker (Atenolol) , ACE inhibitor (Captopril) calcium Channel blocker (Nefidipin ) and diuretics on serum lipid profiles . Method: Thirty untreated hypertensive and 147 hypertensive patient treated with these antihypertensive drugs, attending different public health clinics in Basrah pronivce were enrolled in this study . Serum lipid profile were determined enzymaticaly using kits from BioMerieux, France . Result : The study has revealed that ß-blocker do not significantly affect total cholesterol ( TC ) and LDLcholesterol , but increase significantly triglyceride (TG) and VLDL – cholesterol and decrease HDL – cholesterol. Diuretics causes a significant elevation of TG with generally no significant changes in TC , LDL – cholesterol , VLDL – cholesterol and HDL-cholesterol. ACE inhibitor and calcium channel blockers appears to have no significant effect on plasma lipids . Conclusion :It may important to measure blood lipid levels to identify pre-existing hyperlipidemia before starting the antihypertensive therapy and to select antihypertensive agent that will not influence the lipid profile or interfere with the therapy of hyperlipidemi https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/713Hypertension,lipid and lipid profilesantihypertensive,drugs |
| spellingShingle | Abdul-Khader A. Abdul-Khader Lipid Profile and Antihypertensive Drugs مجله كليه طب الكندي Hypertension, lipid and lipid profiles antihypertensive ,drugs |
| title | Lipid Profile and Antihypertensive Drugs |
| title_full | Lipid Profile and Antihypertensive Drugs |
| title_fullStr | Lipid Profile and Antihypertensive Drugs |
| title_full_unstemmed | Lipid Profile and Antihypertensive Drugs |
| title_short | Lipid Profile and Antihypertensive Drugs |
| title_sort | lipid profile and antihypertensive drugs |
| topic | Hypertension, lipid and lipid profiles antihypertensive ,drugs |
| url | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/713 |
| work_keys_str_mv | AT abdulkhaderaabdulkhader lipidprofileandantihypertensivedrugs |