Treatment of vaginal infections: effectiveness of the association of metronidazole and clotrimazole

The normal vagina of women of reproductive age is colonised by lactobacilli that produce lactic acid, hydrogen peroxide and bacteriocins; these substances contribute to lowering the vaginal pH. A low vaginal pH creates an environment hostile to the growth of other microrganisms. When the number of l...

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Main Author: Simone Ferrero
Format: Article
Language:English
Published: SEEd 2010-03-01
Series:Clinical Management Issues
Subjects:
Online Access:https://journals.seedmedicalpublishers.com/index.php/cmi/article/view/535
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author Simone Ferrero
author_facet Simone Ferrero
author_sort Simone Ferrero
collection DOAJ
description The normal vagina of women of reproductive age is colonised by lactobacilli that produce lactic acid, hydrogen peroxide and bacteriocins; these substances contribute to lowering the vaginal pH. A low vaginal pH creates an environment hostile to the growth of other microrganisms. When the number of lactobacilli is decreased, the resulting increase in the pH may favour vaginal infections. The three most common vaginal infections are bacterial vaginosis, trichomoniasis, and vaginal candidosis. There are multiple clinical and laboratory tests for diagnosing vaginal infections; the most commonly used methods for diagnosing bacterial vaginosis are the Amsel’s criteria and the Nugent’s Gram stain scale. Infections caused by Candida and Trichomonas vaginalis can be diagnosed by microscopic examination of vaginal secretions. Clotrimazole and metronidazole, especially when administered topically, are highly effective in treating vaginal infections.
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spelling doaj.art-af116f91e8eb4e55b9ffbc64759551fa2022-12-21T21:14:59ZengSEEdClinical Management Issues1973-48322283-31372010-03-014171710.7175/cmi.v4i1.535502Treatment of vaginal infections: effectiveness of the association of metronidazole and clotrimazoleSimone Ferrero0Unità Operativa di Ginecologia e Ostetricia, Ospedale San Martino e Università degli Studi di Genova, GenovaThe normal vagina of women of reproductive age is colonised by lactobacilli that produce lactic acid, hydrogen peroxide and bacteriocins; these substances contribute to lowering the vaginal pH. A low vaginal pH creates an environment hostile to the growth of other microrganisms. When the number of lactobacilli is decreased, the resulting increase in the pH may favour vaginal infections. The three most common vaginal infections are bacterial vaginosis, trichomoniasis, and vaginal candidosis. There are multiple clinical and laboratory tests for diagnosing vaginal infections; the most commonly used methods for diagnosing bacterial vaginosis are the Amsel’s criteria and the Nugent’s Gram stain scale. Infections caused by Candida and Trichomonas vaginalis can be diagnosed by microscopic examination of vaginal secretions. Clotrimazole and metronidazole, especially when administered topically, are highly effective in treating vaginal infections.https://journals.seedmedicalpublishers.com/index.php/cmi/article/view/535Bacterial vaginosisClotrimazoleMetronidazoleVaginal candidiasisVaginal infections
spellingShingle Simone Ferrero
Treatment of vaginal infections: effectiveness of the association of metronidazole and clotrimazole
Clinical Management Issues
Bacterial vaginosis
Clotrimazole
Metronidazole
Vaginal candidiasis
Vaginal infections
title Treatment of vaginal infections: effectiveness of the association of metronidazole and clotrimazole
title_full Treatment of vaginal infections: effectiveness of the association of metronidazole and clotrimazole
title_fullStr Treatment of vaginal infections: effectiveness of the association of metronidazole and clotrimazole
title_full_unstemmed Treatment of vaginal infections: effectiveness of the association of metronidazole and clotrimazole
title_short Treatment of vaginal infections: effectiveness of the association of metronidazole and clotrimazole
title_sort treatment of vaginal infections effectiveness of the association of metronidazole and clotrimazole
topic Bacterial vaginosis
Clotrimazole
Metronidazole
Vaginal candidiasis
Vaginal infections
url https://journals.seedmedicalpublishers.com/index.php/cmi/article/view/535
work_keys_str_mv AT simoneferrero treatmentofvaginalinfectionseffectivenessoftheassociationofmetronidazoleandclotrimazole