Methodology for the adolopment of recommendations for the treatment of rheumatoid arthritis in the Kingdom of Saudi Arabia
Abstract Background Currently, there are no guidelines for the treatment of rheumatoid arthritis (RA) tailored to the context of the Kingdom of Saudi Arabia (KSA). Adaptation of guidelines accounts for contextual factors and becomes more efficient than de novo guideline development when relevant, go...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | BMC Medical Research Methodology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12874-023-02031-2 |
| _version_ | 1827633846909140992 |
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| author | Joanne Khabsa Sally Yaacoub Mohammed A. Omair Hanan Al Rayes Elie A. Akl the KSA 2021 ACR RA adolopment working group |
| author_facet | Joanne Khabsa Sally Yaacoub Mohammed A. Omair Hanan Al Rayes Elie A. Akl the KSA 2021 ACR RA adolopment working group |
| author_sort | Joanne Khabsa |
| collection | DOAJ |
| description | Abstract Background Currently, there are no guidelines for the treatment of rheumatoid arthritis (RA) tailored to the context of the Kingdom of Saudi Arabia (KSA). Adaptation of guidelines accounts for contextual factors and becomes more efficient than de novo guideline development when relevant, good quality, and up-to-date guidelines are available. The objective of this study is to describe the methodology used for the adolopment of the 2021 American College of Rheumatology (ACR) guidelines for the treatment of RA in the KSA. Methods We followed the ‘Grading of Recommendations Assessment, Development and Evaluation’ (GRADE)-ADOLOPMENT methodology. The adolopment KSA panel included relevant stakeholders and leading contributors to the original guidelines. We developed a list of five adaptation-relevant prioritization criteria that the panelists applied to the original recommendations. We updated the original evidence profiles with newly published studies identified by the panelists. We constructed Evidence to Decision (EtD) tables including contextual information from the KSA setting. We used the PanelVoice function of GRADEPro Guideline Development Tool (GDT) to obtain the panel’s judgments on the EtD criteria ahead of the panel meeting. Following the meeting, we used the PANELVIEW instrument to obtain the panel’s evaluation of the process. Results The KSA panel prioritized five recommendations, for which one evidence profile required updating. Out of five adoloped recommendations, two were modified in terms of direction, and one was modified in terms of certainty of the evidence. Criteria driving the modifications in direction were valuation of outcomes, balance of effects, cost, and acceptability. The mean score on the 7-point scale items of the PANELVIEW instrument had an average of 6.47 (SD = 0.18) across all items. Conclusion The GRADE-ADOLOPMENT methodology proved to be efficient. The panel assessed the process and outcome positively. Engagement of stakeholders proved to be important for the success of this project. |
| first_indexed | 2024-03-09T15:05:12Z |
| format | Article |
| id | doaj.art-af17f7975fe34d2e93201eb0538ce307 |
| institution | Directory Open Access Journal |
| issn | 1471-2288 |
| language | English |
| last_indexed | 2024-03-09T15:05:12Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medical Research Methodology |
| spelling | doaj.art-af17f7975fe34d2e93201eb0538ce3072023-11-26T13:42:36ZengBMCBMC Medical Research Methodology1471-22882023-10-012311810.1186/s12874-023-02031-2Methodology for the adolopment of recommendations for the treatment of rheumatoid arthritis in the Kingdom of Saudi ArabiaJoanne Khabsa0Sally Yaacoub1Mohammed A. Omair2Hanan Al Rayes3Elie A. Akl4the KSA 2021 ACR RA adolopment working groupAUB Grade Center, American University of Beirut Medical CenterAUB Grade Center, American University of Beirut Medical CenterRheumatology Unit, Department of Medicine, King Saud UniversityDivision of Rheumatology, Department of Internal Medicine, Prince Sultan Military Medical CityDepartment of Internal Medicine, American University of BeirutAbstract Background Currently, there are no guidelines for the treatment of rheumatoid arthritis (RA) tailored to the context of the Kingdom of Saudi Arabia (KSA). Adaptation of guidelines accounts for contextual factors and becomes more efficient than de novo guideline development when relevant, good quality, and up-to-date guidelines are available. The objective of this study is to describe the methodology used for the adolopment of the 2021 American College of Rheumatology (ACR) guidelines for the treatment of RA in the KSA. Methods We followed the ‘Grading of Recommendations Assessment, Development and Evaluation’ (GRADE)-ADOLOPMENT methodology. The adolopment KSA panel included relevant stakeholders and leading contributors to the original guidelines. We developed a list of five adaptation-relevant prioritization criteria that the panelists applied to the original recommendations. We updated the original evidence profiles with newly published studies identified by the panelists. We constructed Evidence to Decision (EtD) tables including contextual information from the KSA setting. We used the PanelVoice function of GRADEPro Guideline Development Tool (GDT) to obtain the panel’s judgments on the EtD criteria ahead of the panel meeting. Following the meeting, we used the PANELVIEW instrument to obtain the panel’s evaluation of the process. Results The KSA panel prioritized five recommendations, for which one evidence profile required updating. Out of five adoloped recommendations, two were modified in terms of direction, and one was modified in terms of certainty of the evidence. Criteria driving the modifications in direction were valuation of outcomes, balance of effects, cost, and acceptability. The mean score on the 7-point scale items of the PANELVIEW instrument had an average of 6.47 (SD = 0.18) across all items. Conclusion The GRADE-ADOLOPMENT methodology proved to be efficient. The panel assessed the process and outcome positively. Engagement of stakeholders proved to be important for the success of this project.https://doi.org/10.1186/s12874-023-02031-2AdaptationAdolopmentContextualizationRheumatoid arthritisAmerican College of RheumatologyKingdom of Saudi Arabia |
| spellingShingle | Joanne Khabsa Sally Yaacoub Mohammed A. Omair Hanan Al Rayes Elie A. Akl the KSA 2021 ACR RA adolopment working group Methodology for the adolopment of recommendations for the treatment of rheumatoid arthritis in the Kingdom of Saudi Arabia BMC Medical Research Methodology Adaptation Adolopment Contextualization Rheumatoid arthritis American College of Rheumatology Kingdom of Saudi Arabia |
| title | Methodology for the adolopment of recommendations for the treatment of rheumatoid arthritis in the Kingdom of Saudi Arabia |
| title_full | Methodology for the adolopment of recommendations for the treatment of rheumatoid arthritis in the Kingdom of Saudi Arabia |
| title_fullStr | Methodology for the adolopment of recommendations for the treatment of rheumatoid arthritis in the Kingdom of Saudi Arabia |
| title_full_unstemmed | Methodology for the adolopment of recommendations for the treatment of rheumatoid arthritis in the Kingdom of Saudi Arabia |
| title_short | Methodology for the adolopment of recommendations for the treatment of rheumatoid arthritis in the Kingdom of Saudi Arabia |
| title_sort | methodology for the adolopment of recommendations for the treatment of rheumatoid arthritis in the kingdom of saudi arabia |
| topic | Adaptation Adolopment Contextualization Rheumatoid arthritis American College of Rheumatology Kingdom of Saudi Arabia |
| url | https://doi.org/10.1186/s12874-023-02031-2 |
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