Co-Delivery of Eugenol and Dacarbazine by Hyaluronic Acid-Coated Liposomes for Targeted Inhibition of Survivin in Treatment of Resistant Metastatic Melanoma

Co-Delivery of Eugenol and Dacarbazine by Hyaluronic Acid-Coated Liposomes for Targeted Inhibition of Survivin in Treatment of Resistant Metastatic Melanoma

While melanoma remains a challenge for oncologists, possibilities are being continuously explored to fight resistant metastatic melanoma more effectively. Eugenol is reported to inhibit survivin protein in breast cancer cells. Survivin is also overexpressed by melanoma cells, and is known to impart...

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Bibliographic Details
Main Authors: Harshita Mishra, Pawan Kumar Mishra, Zeenat Iqbal, Manu Jaggi, Alka Madaan, Kimi Bhuyan, Namita Gupta, Neha Gupta, Karnika Vats, Ritu Verma, Sushama Talegaonkar
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Pharmaceutics
Subjects:
Quality by Design (QbD)
liposomes
hyaluronic acid
melanoma treatment
survivin inhibition
cytotoxicity
apoptosis
migration inhibition
Online Access:https://www.mdpi.com/1999-4923/11/4/163

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