Diabetic neuropathy in the elderly

The increase in the diabetes mellitus (DM) prevalence and incidence has taken on the features of the epidemic. Particularly often, DM occurs in the elderly and senile patients, while at least half of the cases of diabetes in this population remain undiagnosed. DM contributes to the deterioration of...

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Main Authors: Maria А. Cherdak, E. А. Mkhitaryan
Format: Article
Language:Russian
Published: Remedium Group LLC 2020-08-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/5753
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author Maria А. Cherdak
E. А. Mkhitaryan
author_facet Maria А. Cherdak
E. А. Mkhitaryan
author_sort Maria А. Cherdak
collection DOAJ
description The increase in the diabetes mellitus (DM) prevalence and incidence has taken on the features of the epidemic. Particularly often, DM occurs in the elderly and senile patients, while at least half of the cases of diabetes in this population remain undiagnosed. DM contributes to the deterioration of the quality of life, causes formation of dependence and progression of various geriatric syndromes leading to increased mortality. Elderly age is an independent risk factor for diabetic neuropathy. The main clinical forms of which are represented by chronic sensorimotor and autonomic impairments, complicated by impaired cardiovascular, gastrointestinal and urogenital functions, as well as chronic neuropathic pain syndrome. Progression of diabetic neuropathy aggravates walking and balance disorders, increases the risk of falls and loss of mobility, and significantly increases the risk of adverse diabetes outcomes. The article discusses in detail risk factors, pathogenesis, differential diagnosis and the possibilities of clinical and non-clinical evaluation of patients with suspected diabetic neuropathy. Possibilities for pain assessment in elderly people with communicative disorders or concomitant cognitive impairment are demonstrated. The article presents an algorithm for management of diabetic neuropathy in elderly ones, ways for optimization of risk and benefit balance, as well as the possibility of etiopathogenetic and symptomatic treatment of pain, autonomic disorders and prevention of late complications of diabetes with use of alpha-lipouc acid, taking into account key characteristics of discussed population.
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spelling doaj.art-af19a08227f64047bf161d2b2c4e765f2023-04-23T06:56:57ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902020-08-01011536210.21518/2079-701X-2020-11-53-625233Diabetic neuropathy in the elderlyMaria А. Cherdak0E. А. Mkhitaryan1Pirogov Russian National Research Medical UniversityPirogov Russian National Research Medical University; Russian Clinical and Research Center of GerontologyThe increase in the diabetes mellitus (DM) prevalence and incidence has taken on the features of the epidemic. Particularly often, DM occurs in the elderly and senile patients, while at least half of the cases of diabetes in this population remain undiagnosed. DM contributes to the deterioration of the quality of life, causes formation of dependence and progression of various geriatric syndromes leading to increased mortality. Elderly age is an independent risk factor for diabetic neuropathy. The main clinical forms of which are represented by chronic sensorimotor and autonomic impairments, complicated by impaired cardiovascular, gastrointestinal and urogenital functions, as well as chronic neuropathic pain syndrome. Progression of diabetic neuropathy aggravates walking and balance disorders, increases the risk of falls and loss of mobility, and significantly increases the risk of adverse diabetes outcomes. The article discusses in detail risk factors, pathogenesis, differential diagnosis and the possibilities of clinical and non-clinical evaluation of patients with suspected diabetic neuropathy. Possibilities for pain assessment in elderly people with communicative disorders or concomitant cognitive impairment are demonstrated. The article presents an algorithm for management of diabetic neuropathy in elderly ones, ways for optimization of risk and benefit balance, as well as the possibility of etiopathogenetic and symptomatic treatment of pain, autonomic disorders and prevention of late complications of diabetes with use of alpha-lipouc acid, taking into account key characteristics of discussed population.https://www.med-sovet.pro/jour/article/view/5753diabetes mellitusdiabetic neuropathyelderlyneuropathic painautonomic neuropathylipoic acid
spellingShingle Maria А. Cherdak
E. А. Mkhitaryan
Diabetic neuropathy in the elderly
Медицинский совет
diabetes mellitus
diabetic neuropathy
elderly
neuropathic pain
autonomic neuropathy
lipoic acid
title Diabetic neuropathy in the elderly
title_full Diabetic neuropathy in the elderly
title_fullStr Diabetic neuropathy in the elderly
title_full_unstemmed Diabetic neuropathy in the elderly
title_short Diabetic neuropathy in the elderly
title_sort diabetic neuropathy in the elderly
topic diabetes mellitus
diabetic neuropathy
elderly
neuropathic pain
autonomic neuropathy
lipoic acid
url https://www.med-sovet.pro/jour/article/view/5753
work_keys_str_mv AT mariaacherdak diabeticneuropathyintheelderly
AT eamkhitaryan diabeticneuropathyintheelderly