Methylphenidate enhances NMDA-receptor response in medial prefrontal cortex via sigma-1 receptor: a novel mechanism for methylphenidate action.

Methylphenidate (MPH), commercially called Ritalin or Concerta, has been widely used as a drug for Attention Deficit Hyperactivity Disorder (ADHD). Noteworthily, growing numbers of young people using prescribed MPH improperly for pleasurable enhancement, take high risk of addiction. Thus, understand...

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Bibliographic Details
Main Authors: Chun-Lei Zhang, Ze-Jun Feng, Yue Liu, Xiao-Hua Ji, Ji-Yun Peng, Xue-Han Zhang, Xue-Chu Zhen, Bao-Ming Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23284812/?tool=EBI