Trend in blood lead levels in Taiwanese adults 2005-2017.
This study examined the trend of blood lead levels (BLLs) in Taiwanese adults and analyzed the variations in the BLL between Linkou (northern) and Kaohsiung (southern) hospital branches. Between 2005 and 2017, 3,804 adult participants received blood lead tests at the Linkou (n = 2,674) and Kaohsiung...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0260744 |
| _version_ | 1818754876142780416 |
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| author | Chun-Wan Fang Hsiao-Chen Ning Ya-Ching Huang Yu-Shao Chiang Chun-Wei Chuang I-Kuan Wang Nai-Chia Fan Cheng-Hao Weng Wen-Hung Huang Ching-Wei Hsu Tzung-Hai Yen |
| author_facet | Chun-Wan Fang Hsiao-Chen Ning Ya-Ching Huang Yu-Shao Chiang Chun-Wei Chuang I-Kuan Wang Nai-Chia Fan Cheng-Hao Weng Wen-Hung Huang Ching-Wei Hsu Tzung-Hai Yen |
| author_sort | Chun-Wan Fang |
| collection | DOAJ |
| description | This study examined the trend of blood lead levels (BLLs) in Taiwanese adults and analyzed the variations in the BLL between Linkou (northern) and Kaohsiung (southern) hospital branches. Between 2005 and 2017, 3,804 adult participants received blood lead tests at the Linkou (n = 2,674) and Kaohsiung (n = 1,130) branches of Chang Gung Memorial Hospital. The geometric mean of BLL was 2.77 μg/dL. The adult participants from the Kaohsiung branch were not only age older (49.8±14.1 versus 39.4±14.2 years; P<0.001) and male predominant (65.8 versus 41.7%; P<0.001) but also showed a higher BLL (4.45±3.93 versus 2.82±2.42 μg/dL; P<0.001) and lower estimated glomerular filtration rate (87.62±25.94 versus 93.67±23.88; P<0.001) than those from the Linkou branch. Multivariable logistic regression analysis revealed that the Kaohsiung branch [odds ratio (OR): 7.143; 95% confident interval (CI): 5.682-8.929; P<0.001], older age (OR: 1.008; 95% CI: 1.000-1.015; P = 0.043) and reduced estimated glomerular filtration rate (OR: 1.009; 95% CI: 1.004-1.014; P = 0.001) were significant predictors for BLL > 5 μg/dL. Therefore, this study confirmed a continuous decreasing trend in the BLL in Taiwan after banning leaded petrol in 2000. |
| first_indexed | 2024-12-18T05:30:13Z |
| format | Article |
| id | doaj.art-af1b579fff2d48a1ae61d181f5c3757e |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-18T05:30:13Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-af1b579fff2d48a1ae61d181f5c3757e2022-12-21T21:19:27ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-011612e026074410.1371/journal.pone.0260744Trend in blood lead levels in Taiwanese adults 2005-2017.Chun-Wan FangHsiao-Chen NingYa-Ching HuangYu-Shao ChiangChun-Wei ChuangI-Kuan WangNai-Chia FanCheng-Hao WengWen-Hung HuangChing-Wei HsuTzung-Hai YenThis study examined the trend of blood lead levels (BLLs) in Taiwanese adults and analyzed the variations in the BLL between Linkou (northern) and Kaohsiung (southern) hospital branches. Between 2005 and 2017, 3,804 adult participants received blood lead tests at the Linkou (n = 2,674) and Kaohsiung (n = 1,130) branches of Chang Gung Memorial Hospital. The geometric mean of BLL was 2.77 μg/dL. The adult participants from the Kaohsiung branch were not only age older (49.8±14.1 versus 39.4±14.2 years; P<0.001) and male predominant (65.8 versus 41.7%; P<0.001) but also showed a higher BLL (4.45±3.93 versus 2.82±2.42 μg/dL; P<0.001) and lower estimated glomerular filtration rate (87.62±25.94 versus 93.67±23.88; P<0.001) than those from the Linkou branch. Multivariable logistic regression analysis revealed that the Kaohsiung branch [odds ratio (OR): 7.143; 95% confident interval (CI): 5.682-8.929; P<0.001], older age (OR: 1.008; 95% CI: 1.000-1.015; P = 0.043) and reduced estimated glomerular filtration rate (OR: 1.009; 95% CI: 1.004-1.014; P = 0.001) were significant predictors for BLL > 5 μg/dL. Therefore, this study confirmed a continuous decreasing trend in the BLL in Taiwan after banning leaded petrol in 2000.https://doi.org/10.1371/journal.pone.0260744 |
| spellingShingle | Chun-Wan Fang Hsiao-Chen Ning Ya-Ching Huang Yu-Shao Chiang Chun-Wei Chuang I-Kuan Wang Nai-Chia Fan Cheng-Hao Weng Wen-Hung Huang Ching-Wei Hsu Tzung-Hai Yen Trend in blood lead levels in Taiwanese adults 2005-2017. PLoS ONE |
| title | Trend in blood lead levels in Taiwanese adults 2005-2017. |
| title_full | Trend in blood lead levels in Taiwanese adults 2005-2017. |
| title_fullStr | Trend in blood lead levels in Taiwanese adults 2005-2017. |
| title_full_unstemmed | Trend in blood lead levels in Taiwanese adults 2005-2017. |
| title_short | Trend in blood lead levels in Taiwanese adults 2005-2017. |
| title_sort | trend in blood lead levels in taiwanese adults 2005 2017 |
| url | https://doi.org/10.1371/journal.pone.0260744 |
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