Development of a brief screening instrument for emotional distress associated with thromboembolism
Background: Venous thromboembolism (VTE) is associated with emotional distress, including depression, anxiety, fear, and decreased quality of life. A method to rapidly screen patients at increased risk for VTE-related emotional distress could allow providers to facilitate appropriate interventions....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-12-01
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| Series: | Thrombosis Update |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666572720300158 |
| _version_ | 1818411624123334656 |
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| author | Keith S. Keddington Aubrey E. Jones Michael Feehan Daniel M. Witt |
| author_facet | Keith S. Keddington Aubrey E. Jones Michael Feehan Daniel M. Witt |
| author_sort | Keith S. Keddington |
| collection | DOAJ |
| description | Background: Venous thromboembolism (VTE) is associated with emotional distress, including depression, anxiety, fear, and decreased quality of life. A method to rapidly screen patients at increased risk for VTE-related emotional distress could allow providers to facilitate appropriate interventions. Objective: To develop a short, easily administered screening tool that can reliably identify emotional distress in patients recently diagnosed with VTE. Methods: An analysis was performed on data from a national online survey of adult patients with recent VTE. The survey included eight questions developed to assess VTE-related emotional distress, as well as the validated Hospital Anxiety and Depression Scale (HADS). Psychometric analysis was used to evaluate our emotional distress questions for internal consistency and determine associations with HADS Anxiety and Depression subscale scores. Results: A total of 907 surveys were included. Factor analysis of the proposed eight questions identified a single factor with an eigenvalue of 5.42. There was a significant and strong correlation with the HADS Anxiety (HADS-A) and HADS Depression (HADS-D) subscale scores, r = 0.71 and r = 0.57, respectively (both p-values <0.001). A total score of 10 or more using our new emotional distress screening tool correlated with HADS-A and HADS-D scores ≥11 indicating high anxiety and/or depression. Conclusions: We developed and tested a new brief screening tool composed of eight questions that assesses patients for VTE-related emotional distress and is easily administered in a clinical setting. Additional investigations in broader populations and in validation studies are required to confirm these findings and foster the tool’s routine use in clinical practice. |
| first_indexed | 2024-12-14T10:34:22Z |
| format | Article |
| id | doaj.art-af1f6775d227408f96c75f9e5f09c780 |
| institution | Directory Open Access Journal |
| issn | 2666-5727 |
| language | English |
| last_indexed | 2024-12-14T10:34:22Z |
| publishDate | 2020-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Thrombosis Update |
| spelling | doaj.art-af1f6775d227408f96c75f9e5f09c7802022-12-21T23:06:00ZengElsevierThrombosis Update2666-57272020-12-011100015Development of a brief screening instrument for emotional distress associated with thromboembolismKeith S. Keddington0Aubrey E. Jones1Michael Feehan2Daniel M. Witt3University of Utah College of Pharmacy, Department of Pharmacotherapy, 30 S 2000 E, Salt Lake City, UT, 84112, USAUniversity of Utah School of Medicine, Department of Population Health, Williams Building, Room 1N490, 295 Chipeta Way, Salt Lake City, UT, 84108, USAKantar LLC, 3 World Trade Center, 34th Floor, 175 Greenwich Street, New York, NY, 10007, USAUniversity of Utah College of Pharmacy, Department of Pharmacotherapy, 30 S 2000 E, Salt Lake City, UT, 84112, USA; Corresponding author. 30 South 2000 East, Room 4323, University of Utah College of Pharmacy, Salt Lake City, UT 84112, USA.Background: Venous thromboembolism (VTE) is associated with emotional distress, including depression, anxiety, fear, and decreased quality of life. A method to rapidly screen patients at increased risk for VTE-related emotional distress could allow providers to facilitate appropriate interventions. Objective: To develop a short, easily administered screening tool that can reliably identify emotional distress in patients recently diagnosed with VTE. Methods: An analysis was performed on data from a national online survey of adult patients with recent VTE. The survey included eight questions developed to assess VTE-related emotional distress, as well as the validated Hospital Anxiety and Depression Scale (HADS). Psychometric analysis was used to evaluate our emotional distress questions for internal consistency and determine associations with HADS Anxiety and Depression subscale scores. Results: A total of 907 surveys were included. Factor analysis of the proposed eight questions identified a single factor with an eigenvalue of 5.42. There was a significant and strong correlation with the HADS Anxiety (HADS-A) and HADS Depression (HADS-D) subscale scores, r = 0.71 and r = 0.57, respectively (both p-values <0.001). A total score of 10 or more using our new emotional distress screening tool correlated with HADS-A and HADS-D scores ≥11 indicating high anxiety and/or depression. Conclusions: We developed and tested a new brief screening tool composed of eight questions that assesses patients for VTE-related emotional distress and is easily administered in a clinical setting. Additional investigations in broader populations and in validation studies are required to confirm these findings and foster the tool’s routine use in clinical practice.http://www.sciencedirect.com/science/article/pii/S2666572720300158ValidationPsychometricDepressionAnxietyVenous thromboembolism |
| spellingShingle | Keith S. Keddington Aubrey E. Jones Michael Feehan Daniel M. Witt Development of a brief screening instrument for emotional distress associated with thromboembolism Thrombosis Update Validation Psychometric Depression Anxiety Venous thromboembolism |
| title | Development of a brief screening instrument for emotional distress associated with thromboembolism |
| title_full | Development of a brief screening instrument for emotional distress associated with thromboembolism |
| title_fullStr | Development of a brief screening instrument for emotional distress associated with thromboembolism |
| title_full_unstemmed | Development of a brief screening instrument for emotional distress associated with thromboembolism |
| title_short | Development of a brief screening instrument for emotional distress associated with thromboembolism |
| title_sort | development of a brief screening instrument for emotional distress associated with thromboembolism |
| topic | Validation Psychometric Depression Anxiety Venous thromboembolism |
| url | http://www.sciencedirect.com/science/article/pii/S2666572720300158 |
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