Neuroimaging, cognition, light and circadian rhythms
In humans, sleep and wakefulness and the associated cognitive processes are regulated through interactions between sleep homeostasis and the circadian system. Chronic disruption of sleep and circadian rhythmicity is common in our society and there is a need for a better understanding of the brain me...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-07-01
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| Series: | Frontiers in Systems Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00126/full |
| _version_ | 1819023580994732032 |
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| author | Giulia eGaggioni Pierre eMaquet Christina eSchmidt Christina eSchmidt Derk-Jan eDijk Gilles eVandewalle |
| author_facet | Giulia eGaggioni Pierre eMaquet Christina eSchmidt Christina eSchmidt Derk-Jan eDijk Gilles eVandewalle |
| author_sort | Giulia eGaggioni |
| collection | DOAJ |
| description | In humans, sleep and wakefulness and the associated cognitive processes are regulated through interactions between sleep homeostasis and the circadian system. Chronic disruption of sleep and circadian rhythmicity is common in our society and there is a need for a better understanding of the brain mechanisms regulating sleep, wakefulness and associated cognitive processes. This review summarizes recent investigations which provide first neural correlates of the combined influence of sleep homeostasis and circadian rhythmicity on cognitive brain activity. Markers of interindividual variations in sleep-wake regulation, such as chronotype and polymorphisms in sleep and clock genes, are associated with changes in cognitive brain responses in subcortical and cortical areas in response to manipulations of the sleep-wake cycle. This review also includes recent data showing that cognitive brain activity is regulated by light, which is a powerful modulator of cognition and alertness and also directly impacts sleep and circadian rhythmicity. The effect of light varied with age, psychiatric status, PERIOD3 genotype and changes in sleep homeostasis and circadian phase. These data provide new insights into the contribution of demographic characteristics, the sleep-wake cycle, circadian rhythmicity and light to brain functioning. |
| first_indexed | 2024-12-21T04:41:10Z |
| format | Article |
| id | doaj.art-af215683c4174b24aa2ecad85c1b5cec |
| institution | Directory Open Access Journal |
| issn | 1662-5137 |
| language | English |
| last_indexed | 2024-12-21T04:41:10Z |
| publishDate | 2014-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Systems Neuroscience |
| spelling | doaj.art-af215683c4174b24aa2ecad85c1b5cec2022-12-21T19:15:41ZengFrontiers Media S.A.Frontiers in Systems Neuroscience1662-51372014-07-01810.3389/fnsys.2014.0012692031Neuroimaging, cognition, light and circadian rhythmsGiulia eGaggioni0Pierre eMaquet1Christina eSchmidt2Christina eSchmidt3Derk-Jan eDijk4Gilles eVandewalle5Cyclotron Research CentreCyclotron Research CentreCyclotron Research CentreCentre for ChronobiologySurrey Sleep Research CentreCyclotron Research CentreIn humans, sleep and wakefulness and the associated cognitive processes are regulated through interactions between sleep homeostasis and the circadian system. Chronic disruption of sleep and circadian rhythmicity is common in our society and there is a need for a better understanding of the brain mechanisms regulating sleep, wakefulness and associated cognitive processes. This review summarizes recent investigations which provide first neural correlates of the combined influence of sleep homeostasis and circadian rhythmicity on cognitive brain activity. Markers of interindividual variations in sleep-wake regulation, such as chronotype and polymorphisms in sleep and clock genes, are associated with changes in cognitive brain responses in subcortical and cortical areas in response to manipulations of the sleep-wake cycle. This review also includes recent data showing that cognitive brain activity is regulated by light, which is a powerful modulator of cognition and alertness and also directly impacts sleep and circadian rhythmicity. The effect of light varied with age, psychiatric status, PERIOD3 genotype and changes in sleep homeostasis and circadian phase. These data provide new insights into the contribution of demographic characteristics, the sleep-wake cycle, circadian rhythmicity and light to brain functioning.http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00126/fullCognitionLightSleepfMRIcircadiannon-image-forming |
| spellingShingle | Giulia eGaggioni Pierre eMaquet Christina eSchmidt Christina eSchmidt Derk-Jan eDijk Gilles eVandewalle Neuroimaging, cognition, light and circadian rhythms Frontiers in Systems Neuroscience Cognition Light Sleep fMRI circadian non-image-forming |
| title | Neuroimaging, cognition, light and circadian rhythms |
| title_full | Neuroimaging, cognition, light and circadian rhythms |
| title_fullStr | Neuroimaging, cognition, light and circadian rhythms |
| title_full_unstemmed | Neuroimaging, cognition, light and circadian rhythms |
| title_short | Neuroimaging, cognition, light and circadian rhythms |
| title_sort | neuroimaging cognition light and circadian rhythms |
| topic | Cognition Light Sleep fMRI circadian non-image-forming |
| url | http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00126/full |
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