A Case of Recurrent Myocarditis After COVID-19 Vaccination, Due to Acute Myeloid LeukemiaNovel Teaching Points
A 25-year-old man presented with chest pain and an elevated troponin level following COVID-19 vaccination. Despite initial response to nonsteroidal anti-inflammatory drugs, he developed a recurrent and relapsing course requiring multiple readmissions. Cardiac magnetic resonance imaging confirmed myo...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | CJC Open |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589790X22002013 |
| _version_ | 1811293717248606208 |
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| author | Isabelle Dobronyi, MD Danielle Porter, PharmD Idan Roifman, MD Ady Orbach, MD Bradley H. Strauss, MD |
| author_facet | Isabelle Dobronyi, MD Danielle Porter, PharmD Idan Roifman, MD Ady Orbach, MD Bradley H. Strauss, MD |
| author_sort | Isabelle Dobronyi, MD |
| collection | DOAJ |
| description | A 25-year-old man presented with chest pain and an elevated troponin level following COVID-19 vaccination. Despite initial response to nonsteroidal anti-inflammatory drugs, he developed a recurrent and relapsing course requiring multiple readmissions. Cardiac magnetic resonance imaging confirmed myocarditis. Due to progressing macrocytic anemia, he was eventually diagnosed with acute myeloid leukemia, thought to be the underlying driver of his recurrent and persistent myocarditis. Résumé: Nous relatons le cas d’un homme de 25 ans qui présentait une douleur thoracique et un taux élevé de troponine après avoir reçu un vaccin contre la COVID-19. Malgré la réponse initiale du patient aux anti-inflammatoires non stéroïdiens, le tableau clinique a évolué sur un mode récurrent et récidivant, et nécessité plusieurs réhospitalisations. L’imagerie par résonance magnétique cardiaque a permis de confirmer la présence d’une myocardite. Dans un contexte d’anémie macrocytaire évolutive, le patient a finalement reçu un diagnostic de leucémie myéloblastique aiguë, considérée comme le facteur sous-jacent de la myocardite récurrente et persistante dont il était atteint. |
| first_indexed | 2024-04-13T05:06:36Z |
| format | Article |
| id | doaj.art-af25364b75384f0092e81c3d3ce857c7 |
| institution | Directory Open Access Journal |
| issn | 2589-790X |
| language | English |
| last_indexed | 2024-04-13T05:06:36Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | CJC Open |
| spelling | doaj.art-af25364b75384f0092e81c3d3ce857c72022-12-22T03:01:10ZengElsevierCJC Open2589-790X2022-12-0141210271030A Case of Recurrent Myocarditis After COVID-19 Vaccination, Due to Acute Myeloid LeukemiaNovel Teaching PointsIsabelle Dobronyi, MD0Danielle Porter, PharmD1Idan Roifman, MD2Ady Orbach, MD3Bradley H. Strauss, MD4Division of Cardiology, Schulich Heart Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, CanadaDepartment of Pharmacy, Schulich Heart Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, CanadaDivision of Cardiology, Schulich Heart Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, CanadaDivision of Cardiology, Schulich Heart Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, CanadaDivision of Cardiology, Schulich Heart Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada; Corresponding author: Dr Bradley Strauss, Reichmann Chair in Cardiovascular Research, Schulich Heart Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Ave., Suite D4-08, Toronto, Ontario M4N 3M5, Canada. Tel.: +1-416-480-6066; fax: +1-416-480-6066.A 25-year-old man presented with chest pain and an elevated troponin level following COVID-19 vaccination. Despite initial response to nonsteroidal anti-inflammatory drugs, he developed a recurrent and relapsing course requiring multiple readmissions. Cardiac magnetic resonance imaging confirmed myocarditis. Due to progressing macrocytic anemia, he was eventually diagnosed with acute myeloid leukemia, thought to be the underlying driver of his recurrent and persistent myocarditis. Résumé: Nous relatons le cas d’un homme de 25 ans qui présentait une douleur thoracique et un taux élevé de troponine après avoir reçu un vaccin contre la COVID-19. Malgré la réponse initiale du patient aux anti-inflammatoires non stéroïdiens, le tableau clinique a évolué sur un mode récurrent et récidivant, et nécessité plusieurs réhospitalisations. L’imagerie par résonance magnétique cardiaque a permis de confirmer la présence d’une myocardite. Dans un contexte d’anémie macrocytaire évolutive, le patient a finalement reçu un diagnostic de leucémie myéloblastique aiguë, considérée comme le facteur sous-jacent de la myocardite récurrente et persistante dont il était atteint.http://www.sciencedirect.com/science/article/pii/S2589790X22002013 |
| spellingShingle | Isabelle Dobronyi, MD Danielle Porter, PharmD Idan Roifman, MD Ady Orbach, MD Bradley H. Strauss, MD A Case of Recurrent Myocarditis After COVID-19 Vaccination, Due to Acute Myeloid LeukemiaNovel Teaching Points CJC Open |
| title | A Case of Recurrent Myocarditis After COVID-19 Vaccination, Due to Acute Myeloid LeukemiaNovel Teaching Points |
| title_full | A Case of Recurrent Myocarditis After COVID-19 Vaccination, Due to Acute Myeloid LeukemiaNovel Teaching Points |
| title_fullStr | A Case of Recurrent Myocarditis After COVID-19 Vaccination, Due to Acute Myeloid LeukemiaNovel Teaching Points |
| title_full_unstemmed | A Case of Recurrent Myocarditis After COVID-19 Vaccination, Due to Acute Myeloid LeukemiaNovel Teaching Points |
| title_short | A Case of Recurrent Myocarditis After COVID-19 Vaccination, Due to Acute Myeloid LeukemiaNovel Teaching Points |
| title_sort | case of recurrent myocarditis after covid 19 vaccination due to acute myeloid leukemianovel teaching points |
| url | http://www.sciencedirect.com/science/article/pii/S2589790X22002013 |
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