Long non-coding RNA TUG1 knockdown hinders the tumorigenesis of multiple myeloma by regulating the microRNA-34a-5p/NOTCH1 signaling pathway

Long non-coding RNA TUG1 knockdown hinders the tumorigenesis of multiple myeloma by regulating the microRNA-34a-5p/NOTCH1 signaling pathway

Multiple myeloma (MM) is a serious health issue in hematological malignancies. Long non-coding RNA taurine-upregulated gene 1 (TUG1) has been reported to be highly expressed in the plasma of MM patients. However, the functions of TUG1 in MM tumorigenesis along with related molecular basis are still...

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Bibliographic Details
Main Authors: Zhang Yongtian, Zhao Dandan, Li Shumei, Xiao Meng, Zhou Hongjing, Yang Shuige, Hao Yunliang, Dong Shasha
Format: Article
Language:English
Published: De Gruyter 2020-06-01
Series:Open Life Sciences
Subjects:
long non-coding rna
tug1
microrna-34a-5p
notch1
multiple myeloma
Online Access:https://doi.org/10.1515/biol-2020-0025

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