Clinical aspects of hemolysis in patients with P. vivax malaria treated with primaquine, in the Brazilian Amazon
This report describes the development of hemolysis in eighteen glucose-6-phosphate dehydrogenase deficient patients treated for Plasmodium vivax malaria with chloroquine and primaquine. The most frequent findings accompanying hemolysis were fever and leukocytosis, in addition to anemia requiring red...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
|
| Series: | Brazilian Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000400017&lng=en&tlng=en |
| _version_ | 1818119504101638144 |
|---|---|
| author | Wilson M Ramos Júnior José FJ Sardinha Mônica RF Costa Marli S Santana Maria GC Alecrim Marcus VG Lacerda |
| author_facet | Wilson M Ramos Júnior José FJ Sardinha Mônica RF Costa Marli S Santana Maria GC Alecrim Marcus VG Lacerda |
| author_sort | Wilson M Ramos Júnior |
| collection | DOAJ |
| description | This report describes the development of hemolysis in eighteen glucose-6-phosphate dehydrogenase deficient patients treated for Plasmodium vivax malaria with chloroquine and primaquine. The most frequent findings accompanying hemolysis were fever and leukocytosis, in addition to anemia requiring red blood cell transfusion, and development of acute renal failure. Hemolysis in patients using primaquine is not infrequent and contributes to the morbidity of infection caused by Plasmodium vivax. |
| first_indexed | 2024-12-11T05:11:15Z |
| format | Article |
| id | doaj.art-af2b06cfa3e54ec5bc9ff10a4412ab4e |
| institution | Directory Open Access Journal |
| issn | 1678-4391 |
| language | English |
| last_indexed | 2024-12-11T05:11:15Z |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Infectious Diseases |
| spelling | doaj.art-af2b06cfa3e54ec5bc9ff10a4412ab4e2022-12-22T01:19:56ZengElsevierBrazilian Journal of Infectious Diseases1678-439114441041210.1590/S1413-86702010000400017S1413-86702010000400017Clinical aspects of hemolysis in patients with P. vivax malaria treated with primaquine, in the Brazilian AmazonWilson M Ramos Júnior0José FJ Sardinha1Mônica RF Costa2Marli S Santana3Maria GC Alecrim4Marcus VG Lacerda5Fundação de Medicina Tropical Doutor Heitor Vieira DouradoFundação de Medicina Tropical Doutor Heitor Vieira DouradoFundação de Medicina Tropical Doutor Heitor Vieira DouradoUniversidade do Estado do AmazonasUniversidade do Estado do AmazonasFundação de Medicina Tropical Doutor Heitor Vieira DouradoThis report describes the development of hemolysis in eighteen glucose-6-phosphate dehydrogenase deficient patients treated for Plasmodium vivax malaria with chloroquine and primaquine. The most frequent findings accompanying hemolysis were fever and leukocytosis, in addition to anemia requiring red blood cell transfusion, and development of acute renal failure. Hemolysis in patients using primaquine is not infrequent and contributes to the morbidity of infection caused by Plasmodium vivax.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000400017&lng=en&tlng=enmalariaPlasmodium vivaxtreatmentprimaquinehemolysis |
| spellingShingle | Wilson M Ramos Júnior José FJ Sardinha Mônica RF Costa Marli S Santana Maria GC Alecrim Marcus VG Lacerda Clinical aspects of hemolysis in patients with P. vivax malaria treated with primaquine, in the Brazilian Amazon Brazilian Journal of Infectious Diseases malaria Plasmodium vivax treatment primaquine hemolysis |
| title | Clinical aspects of hemolysis in patients with P. vivax malaria treated with primaquine, in the Brazilian Amazon |
| title_full | Clinical aspects of hemolysis in patients with P. vivax malaria treated with primaquine, in the Brazilian Amazon |
| title_fullStr | Clinical aspects of hemolysis in patients with P. vivax malaria treated with primaquine, in the Brazilian Amazon |
| title_full_unstemmed | Clinical aspects of hemolysis in patients with P. vivax malaria treated with primaquine, in the Brazilian Amazon |
| title_short | Clinical aspects of hemolysis in patients with P. vivax malaria treated with primaquine, in the Brazilian Amazon |
| title_sort | clinical aspects of hemolysis in patients with p vivax malaria treated with primaquine in the brazilian amazon |
| topic | malaria Plasmodium vivax treatment primaquine hemolysis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000400017&lng=en&tlng=en |
| work_keys_str_mv | AT wilsonmramosjunior clinicalaspectsofhemolysisinpatientswithpvivaxmalariatreatedwithprimaquineinthebrazilianamazon AT josefjsardinha clinicalaspectsofhemolysisinpatientswithpvivaxmalariatreatedwithprimaquineinthebrazilianamazon AT monicarfcosta clinicalaspectsofhemolysisinpatientswithpvivaxmalariatreatedwithprimaquineinthebrazilianamazon AT marlissantana clinicalaspectsofhemolysisinpatientswithpvivaxmalariatreatedwithprimaquineinthebrazilianamazon AT mariagcalecrim clinicalaspectsofhemolysisinpatientswithpvivaxmalariatreatedwithprimaquineinthebrazilianamazon AT marcusvglacerda clinicalaspectsofhemolysisinpatientswithpvivaxmalariatreatedwithprimaquineinthebrazilianamazon |