Recent Progress in Optical Sensors for Biomedical Diagnostics
In recent years, several types of optical sensors have been probed for their aptitude in healthcare biosensing, making their applications in biomedical diagnostics a rapidly evolving subject. Optical sensors show versatility amongst different receptor types and even permit the integration of differe...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-03-01
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| Series: | Micromachines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-666X/11/4/356 |
| _version_ | 1797571974632833024 |
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| author | Muqsit Pirzada Zeynep Altintas |
| author_facet | Muqsit Pirzada Zeynep Altintas |
| author_sort | Muqsit Pirzada |
| collection | DOAJ |
| description | In recent years, several types of optical sensors have been probed for their aptitude in healthcare biosensing, making their applications in biomedical diagnostics a rapidly evolving subject. Optical sensors show versatility amongst different receptor types and even permit the integration of different detection mechanisms. Such conjugated sensing platforms facilitate the exploitation of their neoteric synergistic characteristics for sensor fabrication. This paper covers nearly 250 research articles since 2016 representing the emerging interest in rapid, reproducible and ultrasensitive assays in clinical analysis. Therefore, we present an elaborate review of biomedical diagnostics with the help of optical sensors working on varied principles such as surface plasmon resonance, localised surface plasmon resonance, evanescent wave fluorescence, bioluminescence and several others. These sensors are capable of investigating toxins, proteins, pathogens, disease biomarkers and whole cells in varied sensing media ranging from water to buffer to more complex environments such as serum, blood or urine. Hence, the recent trends discussed in this review hold enormous potential for the widespread use of optical sensors in early-stage disease prediction and point-of-care testing devices. |
| first_indexed | 2024-03-10T20:48:07Z |
| format | Article |
| id | doaj.art-af2c75bea9be4ddca552e9917a05e768 |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-03-10T20:48:07Z |
| publishDate | 2020-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-af2c75bea9be4ddca552e9917a05e7682023-11-19T20:10:00ZengMDPI AGMicromachines2072-666X2020-03-0111435610.3390/mi11040356Recent Progress in Optical Sensors for Biomedical DiagnosticsMuqsit Pirzada0Zeynep Altintas1Institute of Chemistry, Technical University of Berlin, Straße des 17. Juni 124, 10623 Berlin, GermanyInstitute of Chemistry, Technical University of Berlin, Straße des 17. Juni 124, 10623 Berlin, GermanyIn recent years, several types of optical sensors have been probed for their aptitude in healthcare biosensing, making their applications in biomedical diagnostics a rapidly evolving subject. Optical sensors show versatility amongst different receptor types and even permit the integration of different detection mechanisms. Such conjugated sensing platforms facilitate the exploitation of their neoteric synergistic characteristics for sensor fabrication. This paper covers nearly 250 research articles since 2016 representing the emerging interest in rapid, reproducible and ultrasensitive assays in clinical analysis. Therefore, we present an elaborate review of biomedical diagnostics with the help of optical sensors working on varied principles such as surface plasmon resonance, localised surface plasmon resonance, evanescent wave fluorescence, bioluminescence and several others. These sensors are capable of investigating toxins, proteins, pathogens, disease biomarkers and whole cells in varied sensing media ranging from water to buffer to more complex environments such as serum, blood or urine. Hence, the recent trends discussed in this review hold enormous potential for the widespread use of optical sensors in early-stage disease prediction and point-of-care testing devices.https://www.mdpi.com/2072-666X/11/4/356optical sensorsbiomedical diagnosticssurface plasmon resonanceevanescent wavebioluminescenceellipsometry |
| spellingShingle | Muqsit Pirzada Zeynep Altintas Recent Progress in Optical Sensors for Biomedical Diagnostics Micromachines optical sensors biomedical diagnostics surface plasmon resonance evanescent wave bioluminescence ellipsometry |
| title | Recent Progress in Optical Sensors for Biomedical Diagnostics |
| title_full | Recent Progress in Optical Sensors for Biomedical Diagnostics |
| title_fullStr | Recent Progress in Optical Sensors for Biomedical Diagnostics |
| title_full_unstemmed | Recent Progress in Optical Sensors for Biomedical Diagnostics |
| title_short | Recent Progress in Optical Sensors for Biomedical Diagnostics |
| title_sort | recent progress in optical sensors for biomedical diagnostics |
| topic | optical sensors biomedical diagnostics surface plasmon resonance evanescent wave bioluminescence ellipsometry |
| url | https://www.mdpi.com/2072-666X/11/4/356 |
| work_keys_str_mv | AT muqsitpirzada recentprogressinopticalsensorsforbiomedicaldiagnostics AT zeynepaltintas recentprogressinopticalsensorsforbiomedicaldiagnostics |