The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges
A considerable number of clinical trials is being conducted globally in response to the COVID-19 pandemic, including in low- and middle-income countries such as those in the Latin America and Caribbean region (LAC). Yet, an abundance of studies does not necessarily shorten the path to find safe and...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Pan American Health Organization
2020-12-01
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| Series: | Revista Panamericana de Salud Pública |
| Subjects: | |
| Online Access: | https://iris.paho.org/handle/10665.2/53150 |
| _version_ | 1818565660704243712 |
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| author | Sarah Carracedo Ana Palmero Marcie Neil Anisa Hasan-Granier Carla Saenz Ludovic Reveiz |
| author_facet | Sarah Carracedo Ana Palmero Marcie Neil Anisa Hasan-Granier Carla Saenz Ludovic Reveiz |
| author_sort | Sarah Carracedo |
| collection | DOAJ |
| description | A considerable number of clinical trials is being conducted globally in response to the COVID-19 pandemic, including in low- and middle-income countries such as those in the Latin America and Caribbean region (LAC). Yet, an abundance of studies does not necessarily shorten the path to find safe and efficacious interventions for COVID-19. We analyze the trials for COVID-19 treatment and prevention that are registered from LAC countries in the International Clinical Trials Registry Platform, and identify a trend towards small repetitive non-rigorous studies that duplicate efforts and drain limited resources without producing meaningful conclusions on the safety and efficacy of the interventions being tested. We further assess the challenges to conducting scientifically sound and socially valuable research in the LAC region in order to inform recommendations to encourage clinical trials that are most likely to produce robust evidence during the pandemic. |
| first_indexed | 2024-12-14T01:44:07Z |
| format | Article |
| id | doaj.art-af2e6b3715654ec99e57018e7b6ba8f9 |
| institution | Directory Open Access Journal |
| issn | 1020-4989 1680-5348 |
| language | English |
| last_indexed | 2024-12-14T01:44:07Z |
| publishDate | 2020-12-01 |
| publisher | Pan American Health Organization |
| record_format | Article |
| series | Revista Panamericana de Salud Pública |
| spelling | doaj.art-af2e6b3715654ec99e57018e7b6ba8f92022-12-21T23:21:37ZengPan American Health OrganizationRevista Panamericana de Salud Pública1020-49891680-53482020-12-01441771510.26633/RPSP.2020.177rpspThe landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challengesSarah Carracedo0Ana Palmero1Marcie Neil2Anisa Hasan-Granier3Carla Saenz4Ludovic Reveiz5Pan American Health Organization, Washington, DC, United States of America.Pan American Health Organization, Washington, DC, United States of America.Pan American Health Organization, Washington, DC, United States of America.Pan American Health Organization, Washington, DC, United States of America.Pan American Health Organization, Washington, DC, United States of America.Pan American Health Organization, Washington, DC, United States of America.A considerable number of clinical trials is being conducted globally in response to the COVID-19 pandemic, including in low- and middle-income countries such as those in the Latin America and Caribbean region (LAC). Yet, an abundance of studies does not necessarily shorten the path to find safe and efficacious interventions for COVID-19. We analyze the trials for COVID-19 treatment and prevention that are registered from LAC countries in the International Clinical Trials Registry Platform, and identify a trend towards small repetitive non-rigorous studies that duplicate efforts and drain limited resources without producing meaningful conclusions on the safety and efficacy of the interventions being tested. We further assess the challenges to conducting scientifically sound and socially valuable research in the LAC region in order to inform recommendations to encourage clinical trials that are most likely to produce robust evidence during the pandemic.https://iris.paho.org/handle/10665.2/53150coronavirus infectionsclinical trialethics, researchpublic health policylatin americacaribbean region |
| spellingShingle | Sarah Carracedo Ana Palmero Marcie Neil Anisa Hasan-Granier Carla Saenz Ludovic Reveiz The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges Revista Panamericana de Salud Pública coronavirus infections clinical trial ethics, research public health policy latin america caribbean region |
| title | The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges |
| title_full | The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges |
| title_fullStr | The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges |
| title_full_unstemmed | The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges |
| title_short | The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges |
| title_sort | landscape of covid 19 clinical trials in latin america and the caribbean assessment and challenges |
| topic | coronavirus infections clinical trial ethics, research public health policy latin america caribbean region |
| url | https://iris.paho.org/handle/10665.2/53150 |
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