Retinal detachments in a patient with minimal change nephrotic syndrome: Case report and review of the literature

BackgroundTo report an unusual case of minimal change nephrotic syndrome with sudden bilateral retinal detachment.Case presentationA 54-year-old woman with minimal change nephrotic syndrome presented with sudden-onset visual blurring in both eyes. Optical coherence tomography scans revealed macular...

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Main Authors: Chunjian Ye, Miaohua Qiu, Yu Zhong, Jiejian Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Nephrology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneph.2022.1070792/full
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author Chunjian Ye
Miaohua Qiu
Yu Zhong
Jiejian Chen
author_facet Chunjian Ye
Miaohua Qiu
Yu Zhong
Jiejian Chen
author_sort Chunjian Ye
collection DOAJ
description BackgroundTo report an unusual case of minimal change nephrotic syndrome with sudden bilateral retinal detachment.Case presentationA 54-year-old woman with minimal change nephrotic syndrome presented with sudden-onset visual blurring in both eyes. Optical coherence tomography scans revealed macular schisis and extramacular intraretinal separation. A kidney biopsy confirmed the diagnosis of minimal change disease. Glucocorticoid therapy was quickly started. During remission, her vision was restored, with complete resolution of the subretinal fluid observed on optical coherence tomography.ConclusionsIn minimal change nephrotic syndrome, fluid accumulation in the retina layer may occur, and gravity-induced vitreous traction on the inferior retina may cause retinal detachment. Patients should be advised to avoid large swings of the head and neck, handstands, and other activities that may increase the risk of retinal detachment. The possibility of retinal detachment should be considered when blurred vision occurs.
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spelling doaj.art-af305683277d4782ad23341b73aed0172023-01-18T05:33:24ZengFrontiers Media S.A.Frontiers in Nephrology2813-06262023-01-01210.3389/fneph.2022.10707921070792Retinal detachments in a patient with minimal change nephrotic syndrome: Case report and review of the literatureChunjian YeMiaohua QiuYu ZhongJiejian ChenBackgroundTo report an unusual case of minimal change nephrotic syndrome with sudden bilateral retinal detachment.Case presentationA 54-year-old woman with minimal change nephrotic syndrome presented with sudden-onset visual blurring in both eyes. Optical coherence tomography scans revealed macular schisis and extramacular intraretinal separation. A kidney biopsy confirmed the diagnosis of minimal change disease. Glucocorticoid therapy was quickly started. During remission, her vision was restored, with complete resolution of the subretinal fluid observed on optical coherence tomography.ConclusionsIn minimal change nephrotic syndrome, fluid accumulation in the retina layer may occur, and gravity-induced vitreous traction on the inferior retina may cause retinal detachment. Patients should be advised to avoid large swings of the head and neck, handstands, and other activities that may increase the risk of retinal detachment. The possibility of retinal detachment should be considered when blurred vision occurs.https://www.frontiersin.org/articles/10.3389/fneph.2022.1070792/fullminimal change diseaseretinal detachmentnephrotic syndromeedemahypoproteinemia
spellingShingle Chunjian Ye
Miaohua Qiu
Yu Zhong
Jiejian Chen
Retinal detachments in a patient with minimal change nephrotic syndrome: Case report and review of the literature
Frontiers in Nephrology
minimal change disease
retinal detachment
nephrotic syndrome
edema
hypoproteinemia
title Retinal detachments in a patient with minimal change nephrotic syndrome: Case report and review of the literature
title_full Retinal detachments in a patient with minimal change nephrotic syndrome: Case report and review of the literature
title_fullStr Retinal detachments in a patient with minimal change nephrotic syndrome: Case report and review of the literature
title_full_unstemmed Retinal detachments in a patient with minimal change nephrotic syndrome: Case report and review of the literature
title_short Retinal detachments in a patient with minimal change nephrotic syndrome: Case report and review of the literature
title_sort retinal detachments in a patient with minimal change nephrotic syndrome case report and review of the literature
topic minimal change disease
retinal detachment
nephrotic syndrome
edema
hypoproteinemia
url https://www.frontiersin.org/articles/10.3389/fneph.2022.1070792/full
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