Steep Decline in Binding Capability of SARS-CoV-2 Omicron Variant (B.1.1.529) RBD to the Antibodies in Early COVID-19 Convalescent Sera and Inactivated Vaccine Sera

Steep Decline in Binding Capability of SARS-CoV-2 Omicron Variant (B.1.1.529) RBD to the Antibodies in Early COVID-19 Convalescent Sera and Inactivated Vaccine Sera

A new SARS-CoV-2 variant B.1.1.529 was named by the WHO as Omicron and classified as a Variant of Concern (VOC) on 26 November 2021. Because this variant has more than 50 mutations, including 30 mutations on the spike, it has generated a lot of concerns on the potential impacts of the VOC on COVID-1...

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Bibliographic Details
Main Authors: Wenhao Zhou, Ping He, Junhua Li, Huan Liu, Mengjuan Shi, Junping Yu, Hongping Wei
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Viruses
Subjects:
SARS-CoV-2
Omicron
variants of concern
antibody
receptor-binding domain
inactivated vaccine
Online Access:https://www.mdpi.com/1999-4915/14/2/335

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