Assessment of bidirectional relationships between brain imaging-derived phenotypes and stroke: a Mendelian randomization study

Assessment of bidirectional relationships between brain imaging-derived phenotypes and stroke: a Mendelian randomization study

Abstract Background Stroke is a major cause of mortality and long-term disability worldwide. Whether the associations between brain imaging-derived phenotypes (IDPs) and stroke are causal is uncertain. Methods We performed two-sample bidirectional Mendelian randomization (MR) analyses to explore the...

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Bibliographic Details
Main Authors: Ke Yu, Xiao-Feng Chen, Jing Guo, Sen Wang, Xiao-Ting Huang, Yan Guo, Shan-Shan Dong, Tie-Lin Yang
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Medicine
Subjects:
Stroke
IDPs
Causal association
Mendelian randomization
Online Access:https://doi.org/10.1186/s12916-023-02982-9

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