Role of CCL2/MCP-1 in Islet Transplantation
High levels of donor-derived CCL2 have been associated with poor islet allograft outcome in patients with type 1 diabetes. The aim of our work was to determine whether CCL2 secreted by the islet has independent proinflammatory effects that influence engraftment and graft acceptance. Both in mice and...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2010-08-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368910X514639 |