Evolving Pandemic Diabetic Nephropathy

The expanding impact of chronic kidney disease (CKD) due to pandemic diabetes mellitus is recounted emphasizing its epidemiology that has induced global socioeconomic stress on health care systems in industrialized nations now attempting to proffer optimal therapy for end stage renal disease (ESRD)....

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Main Author: Eli A. Friedman
Format: Article
Language:English
Published: Rambam Health Care Campus 2010-07-01
Series:Rambam Maimonides Medical Journal
Subjects:
Online Access:http://rmmj.org.il/(S(qh3lmpohu1o4cvqqcnfhxlye))/Pages/ArticleHTM.aspx?manuId=6
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author Eli A. Friedman
author_facet Eli A. Friedman
author_sort Eli A. Friedman
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description The expanding impact of chronic kidney disease (CKD) due to pandemic diabetes mellitus is recounted emphasizing its epidemiology that has induced global socioeconomic stress on health care systems in industrialized nations now attempting to proffer optimal therapy for end stage renal disease (ESRD). Strategies to delay and perhaps prevent progression of diabetic nephropathy from minimal proteinuria through nephrotic range proteinuria and azotemia to ESRD appear to have decreased the rate of persons with diabetes who develop ESRD. For those with ESRD attributed to diabetes, kidney transplantation affords better survival and rehabilitation than either hemodialysis or peritoneal dialysis. It is likely that advances in genetics and molecular biology will suggest early interventions that will preempt diabetic complications including renal failure.
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spelling doaj.art-af38437cca534396b01989204644cf8d2022-12-21T23:56:48ZengRambam Health Care CampusRambam Maimonides Medical Journal2076-91722010-07-0111e000510.5041/RMMJ.10005Evolving Pandemic Diabetic NephropathyEli A. Friedman0Distinguished Teaching Professor of Medicine, Downstate Medical Center, Brooklyn, New York, USAThe expanding impact of chronic kidney disease (CKD) due to pandemic diabetes mellitus is recounted emphasizing its epidemiology that has induced global socioeconomic stress on health care systems in industrialized nations now attempting to proffer optimal therapy for end stage renal disease (ESRD). Strategies to delay and perhaps prevent progression of diabetic nephropathy from minimal proteinuria through nephrotic range proteinuria and azotemia to ESRD appear to have decreased the rate of persons with diabetes who develop ESRD. For those with ESRD attributed to diabetes, kidney transplantation affords better survival and rehabilitation than either hemodialysis or peritoneal dialysis. It is likely that advances in genetics and molecular biology will suggest early interventions that will preempt diabetic complications including renal failure.http://rmmj.org.il/(S(qh3lmpohu1o4cvqqcnfhxlye))/Pages/ArticleHTM.aspx?manuId=6diabetic nephropathychronic kidney diseaseglycationrenal failurerenoprotection
spellingShingle Eli A. Friedman
Evolving Pandemic Diabetic Nephropathy
Rambam Maimonides Medical Journal
diabetic nephropathy
chronic kidney disease
glycation
renal failure
renoprotection
title Evolving Pandemic Diabetic Nephropathy
title_full Evolving Pandemic Diabetic Nephropathy
title_fullStr Evolving Pandemic Diabetic Nephropathy
title_full_unstemmed Evolving Pandemic Diabetic Nephropathy
title_short Evolving Pandemic Diabetic Nephropathy
title_sort evolving pandemic diabetic nephropathy
topic diabetic nephropathy
chronic kidney disease
glycation
renal failure
renoprotection
url http://rmmj.org.il/(S(qh3lmpohu1o4cvqqcnfhxlye))/Pages/ArticleHTM.aspx?manuId=6
work_keys_str_mv AT eliafriedman evolvingpandemicdiabeticnephropathy