Is It Possible to Personalize the Diagnosis and Treatment of Breast Cancer during Pregnancy?
The main goal of precision medicine in patients with breast cancer is to tailor the treatment according to the particular genetic makeup and the genetic changes in the cancer cells. Breast cancer occurring during pregnancy (BCP) is a complex and difficult clinical problem. Although it is not very co...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-12-01
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| Series: | Journal of Personalized Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4426/11/1/18 |
| _version_ | 1797543317762736128 |
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| author | Petra Tesarova David Pavlista Antonin Parizek |
| author_facet | Petra Tesarova David Pavlista Antonin Parizek |
| author_sort | Petra Tesarova |
| collection | DOAJ |
| description | The main goal of precision medicine in patients with breast cancer is to tailor the treatment according to the particular genetic makeup and the genetic changes in the cancer cells. Breast cancer occurring during pregnancy (BCP) is a complex and difficult clinical problem. Although it is not very common, both maternal and fetal outcome must be always considered when planning treatment. Pregnancy represents a significant barrier to the implementation of personalized treatment for breast cancer. Tailoring therapy mainly takes into account the stage of pregnancy, the subtype of cancer, the stage of cancer, and the patient’s preference. Results of the treatment of breast cancer in pregnancy are as yet not very satisfactory because of often delayed diagnosis, and it usually has an unfavorable outcome. Treatment of patients with pregnancy-associated breast cancer should be centralized. Centralization may result in increased experience in diagnosis and treatment and accumulated data may help us to optimize the treatment approaches, modify general treatment recommendations, and improve the survival and quality of life of the patients. |
| first_indexed | 2024-03-10T13:42:53Z |
| format | Article |
| id | doaj.art-af3d70570ea1447ab8f397b47cd284e1 |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-10T13:42:53Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-af3d70570ea1447ab8f397b47cd284e12023-11-21T02:52:27ZengMDPI AGJournal of Personalized Medicine2075-44262020-12-011111810.3390/jpm11010018Is It Possible to Personalize the Diagnosis and Treatment of Breast Cancer during Pregnancy?Petra Tesarova0David Pavlista1Antonin Parizek2Department of Oncology, 1st Faculty of Medicine Charles University and General University Hospital, 128 08 Prague, Czech RepublicDepartment of Gynecology and Obstetrics, 1st Faculty of Medicine Charles University and General University Hospital, 128 08 Prague, Czech RepublicDepartment of Gynecology and Obstetrics, 1st Faculty of Medicine Charles University and General University Hospital, 128 08 Prague, Czech RepublicThe main goal of precision medicine in patients with breast cancer is to tailor the treatment according to the particular genetic makeup and the genetic changes in the cancer cells. Breast cancer occurring during pregnancy (BCP) is a complex and difficult clinical problem. Although it is not very common, both maternal and fetal outcome must be always considered when planning treatment. Pregnancy represents a significant barrier to the implementation of personalized treatment for breast cancer. Tailoring therapy mainly takes into account the stage of pregnancy, the subtype of cancer, the stage of cancer, and the patient’s preference. Results of the treatment of breast cancer in pregnancy are as yet not very satisfactory because of often delayed diagnosis, and it usually has an unfavorable outcome. Treatment of patients with pregnancy-associated breast cancer should be centralized. Centralization may result in increased experience in diagnosis and treatment and accumulated data may help us to optimize the treatment approaches, modify general treatment recommendations, and improve the survival and quality of life of the patients.https://www.mdpi.com/2075-4426/11/1/18breast cancerpregnancychemotherapytailoringpersonalization |
| spellingShingle | Petra Tesarova David Pavlista Antonin Parizek Is It Possible to Personalize the Diagnosis and Treatment of Breast Cancer during Pregnancy? Journal of Personalized Medicine breast cancer pregnancy chemotherapy tailoring personalization |
| title | Is It Possible to Personalize the Diagnosis and Treatment of Breast Cancer during Pregnancy? |
| title_full | Is It Possible to Personalize the Diagnosis and Treatment of Breast Cancer during Pregnancy? |
| title_fullStr | Is It Possible to Personalize the Diagnosis and Treatment of Breast Cancer during Pregnancy? |
| title_full_unstemmed | Is It Possible to Personalize the Diagnosis and Treatment of Breast Cancer during Pregnancy? |
| title_short | Is It Possible to Personalize the Diagnosis and Treatment of Breast Cancer during Pregnancy? |
| title_sort | is it possible to personalize the diagnosis and treatment of breast cancer during pregnancy |
| topic | breast cancer pregnancy chemotherapy tailoring personalization |
| url | https://www.mdpi.com/2075-4426/11/1/18 |
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