Cyto-Histological Manifestations of the Apoptotic Process in the Prepubescent Mouse Ovary (14-17 days)
Follicular atresia is a process commonly encountered at ovarian level that limits the number of ovulations and, respectively, the reproductive potential of a female. Ovarian cells’ death is essential for maintaining homeostasis of this organ and is based on an apoptotic mechanism that ensures select...
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| Format: | Article |
| Language: | English |
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Agroprint Timisoara
2023-09-01
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| Series: | Scientific Papers Animal Science and Biotechnologies |
| Subjects: | |
| Online Access: | https://spasb.ro/index.php/public_html/article/view/260 |
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| author | Liliana Petculescu-Ciochina Gabi Dumitrescu Nicolae Păcala Dorel Dronca Adela Marcu Ioan Bencsik |
| author_facet | Liliana Petculescu-Ciochina Gabi Dumitrescu Nicolae Păcala Dorel Dronca Adela Marcu Ioan Bencsik |
| author_sort | Liliana Petculescu-Ciochina |
| collection | DOAJ |
| description | Follicular atresia is a process commonly encountered at ovarian level that limits the number of ovulations and, respectively, the reproductive potential of a female. Ovarian cells’ death is essential for maintaining homeostasis of this organ and is based on an apoptotic mechanism that ensures selection of the dominant follicle and the disappearance of follicles in excess. The present study evaluates the incidence of morphological changes specific for this process in the prepubescent mouse ovary by applying optical microscopy techniques. Microscopic analysis was performed on sections of ovarian tissue from mice females’ line NMRI aged 14-17 days. The results show, at this age, significant morphological changes at cellular level, specific for apoptotic process, as condensation and fragmentation of the genetic material, vacuolization of cell cytoplasm, destabilization of cell adhesion junctions and appearance of wide intercellular spaces, invasion of created spaces with infiltrated leukocytes, formation of apoptotic bodies. |
| first_indexed | 2024-04-24T11:19:33Z |
| format | Article |
| id | doaj.art-af42152e18d64d85ac2038552ccd37f5 |
| institution | Directory Open Access Journal |
| issn | 1841-9364 2344-4576 |
| language | English |
| last_indexed | 2024-04-24T11:19:33Z |
| publishDate | 2023-09-01 |
| publisher | Agroprint Timisoara |
| record_format | Article |
| series | Scientific Papers Animal Science and Biotechnologies |
| spelling | doaj.art-af42152e18d64d85ac2038552ccd37f52024-04-11T04:59:52ZengAgroprint TimisoaraScientific Papers Animal Science and Biotechnologies1841-93642344-45762023-09-01481205205260Cyto-Histological Manifestations of the Apoptotic Process in the Prepubescent Mouse Ovary (14-17 days)Liliana Petculescu-Ciochina0Gabi Dumitrescu1Nicolae Păcala2Dorel Dronca3Adela Marcu4Ioan Bencsik5Banat’s University of Agricultural Sciences and Veterinary Medicine, King Michael I of Romania from Timişoara, Faculty of Animal Science and Biotechnologies, 300645-Timisoara, Calea Aradului 119, RomaniaBanat’s University of Agricultural Sciences and Veterinary Medicine, King Michael I of Romania from Timişoara, Faculty of Animal Science and Biotechnologies, 300645-Timisoara, Calea Aradului 119, RomaniaBanat’s University of Agricultural Sciences and Veterinary Medicine, King Michael I of Romania from Timişoara, Faculty of Animal Science and Biotechnologies, 300645-Timisoara, Calea Aradului 119, RomaniaBanat’s University of Agricultural Sciences and Veterinary Medicine, King Michael I of Romania from Timişoara, Faculty of Animal Science and Biotechnologies, 300645-Timisoara, Calea Aradului 119, RomaniaBanat’s University of Agricultural Sciences and Veterinary Medicine, King Michael I of Romania from Timişoara, Faculty of Animal Science and Biotechnologies, 300645-Timisoara, Calea Aradului 119, RomaniaBanat’s University of Agricultural Sciences and Veterinary Medicine, King Michael I of Romania from Timişoara, Faculty of Animal Science and Biotechnologies, 300645-Timisoara, Calea Aradului 119, RomaniaFollicular atresia is a process commonly encountered at ovarian level that limits the number of ovulations and, respectively, the reproductive potential of a female. Ovarian cells’ death is essential for maintaining homeostasis of this organ and is based on an apoptotic mechanism that ensures selection of the dominant follicle and the disappearance of follicles in excess. The present study evaluates the incidence of morphological changes specific for this process in the prepubescent mouse ovary by applying optical microscopy techniques. Microscopic analysis was performed on sections of ovarian tissue from mice females’ line NMRI aged 14-17 days. The results show, at this age, significant morphological changes at cellular level, specific for apoptotic process, as condensation and fragmentation of the genetic material, vacuolization of cell cytoplasm, destabilization of cell adhesion junctions and appearance of wide intercellular spaces, invasion of created spaces with infiltrated leukocytes, formation of apoptotic bodies.https://spasb.ro/index.php/public_html/article/view/260apoptosisfolliclesmorphological changesprepubescent mouse ovary |
| spellingShingle | Liliana Petculescu-Ciochina Gabi Dumitrescu Nicolae Păcala Dorel Dronca Adela Marcu Ioan Bencsik Cyto-Histological Manifestations of the Apoptotic Process in the Prepubescent Mouse Ovary (14-17 days) Scientific Papers Animal Science and Biotechnologies apoptosis follicles morphological changes prepubescent mouse ovary |
| title | Cyto-Histological Manifestations of the Apoptotic Process in the Prepubescent Mouse Ovary (14-17 days) |
| title_full | Cyto-Histological Manifestations of the Apoptotic Process in the Prepubescent Mouse Ovary (14-17 days) |
| title_fullStr | Cyto-Histological Manifestations of the Apoptotic Process in the Prepubescent Mouse Ovary (14-17 days) |
| title_full_unstemmed | Cyto-Histological Manifestations of the Apoptotic Process in the Prepubescent Mouse Ovary (14-17 days) |
| title_short | Cyto-Histological Manifestations of the Apoptotic Process in the Prepubescent Mouse Ovary (14-17 days) |
| title_sort | cyto histological manifestations of the apoptotic process in the prepubescent mouse ovary 14 17 days |
| topic | apoptosis follicles morphological changes prepubescent mouse ovary |
| url | https://spasb.ro/index.php/public_html/article/view/260 |
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