TERNARY COMPLEX FORMATION OF ISONIAZID WITH SOME TRANSITION METALS AND AMINO ACIDS
In this article mixed ligand complex formation equilibria of copper(II) and zinc(II) with isoniazid and two amino acids have been determined by potentiometric titration method, involving the use of Irving Rossotti procedure. The formation constants of mixed ligand complexes have been found to be Cu(...
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| Format: | Article |
| Language: | English |
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Trakya University
2016-11-01
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| Series: | Trakya University Journal of Natural Sciences |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/en/download/article-file/234510 |
| _version_ | 1797633890391687168 |
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| author | Bilgiç Alkaya Serap Karaderi Gülbin Erdoğan |
| author_facet | Bilgiç Alkaya Serap Karaderi Gülbin Erdoğan |
| author_sort | Bilgiç Alkaya |
| collection | DOAJ |
| description | In this article mixed ligand complex formation equilibria of copper(II) and zinc(II) with isoniazid and two amino acids have been determined by potentiometric titration method, involving the use of Irving Rossotti procedure. The formation constants of mixed ligand complexes have been found to be Cu(II)-isoniazid-L-asparagine logK= 7.29; Zn(II)- isoniazid-L-asparagine logK= 4.09 and Cu(II)-isoniazid-L-glutamic acid logK= 6.70; Zn(II)- isoniazid-L-glutamic acid logK= 6.30, at 25.0±0.1° C and I= 0.11 mol dm-3 ionic strength (NaCIO4) in aqueous solution. The maximum values of the conditional formation constants were found to be in accordance with the mixed-ligand complex formation constants in a given pH region. In addition, the mole fractions of different species from mixed complexes were calculated by means of formation constants. |
| first_indexed | 2024-03-11T11:59:57Z |
| format | Article |
| id | doaj.art-af438eb036f34181839d770125d04e7e |
| institution | Directory Open Access Journal |
| issn | 2528-9691 |
| language | English |
| last_indexed | 2024-03-11T11:59:57Z |
| publishDate | 2016-11-01 |
| publisher | Trakya University |
| record_format | Article |
| series | Trakya University Journal of Natural Sciences |
| spelling | doaj.art-af438eb036f34181839d770125d04e7e2023-11-08T07:27:57ZengTrakya UniversityTrakya University Journal of Natural Sciences2528-96912016-11-0114111469TERNARY COMPLEX FORMATION OF ISONIAZID WITH SOME TRANSITION METALS AND AMINO ACIDSBilgiç AlkayaSerap KaraderiGülbin ErdoğanIn this article mixed ligand complex formation equilibria of copper(II) and zinc(II) with isoniazid and two amino acids have been determined by potentiometric titration method, involving the use of Irving Rossotti procedure. The formation constants of mixed ligand complexes have been found to be Cu(II)-isoniazid-L-asparagine logK= 7.29; Zn(II)- isoniazid-L-asparagine logK= 4.09 and Cu(II)-isoniazid-L-glutamic acid logK= 6.70; Zn(II)- isoniazid-L-glutamic acid logK= 6.30, at 25.0±0.1° C and I= 0.11 mol dm-3 ionic strength (NaCIO4) in aqueous solution. The maximum values of the conditional formation constants were found to be in accordance with the mixed-ligand complex formation constants in a given pH region. In addition, the mole fractions of different species from mixed complexes were calculated by means of formation constants.https://dergipark.org.tr/en/download/article-file/234510: i̇soniazidl-asparajinl-glutamik asitmetal komplekspotansiyometrikararlılık sabitiisoniazidl-asparaginel-glutamic acidmetal complexsatibility constant |
| spellingShingle | Bilgiç Alkaya Serap Karaderi Gülbin Erdoğan TERNARY COMPLEX FORMATION OF ISONIAZID WITH SOME TRANSITION METALS AND AMINO ACIDS Trakya University Journal of Natural Sciences : i̇soniazid l-asparajin l-glutamik asit metal kompleks potansiyometri kararlılık sabiti isoniazid l-asparagine l-glutamic acid metal complex satibility constant |
| title | TERNARY COMPLEX FORMATION OF ISONIAZID WITH SOME TRANSITION METALS AND AMINO ACIDS |
| title_full | TERNARY COMPLEX FORMATION OF ISONIAZID WITH SOME TRANSITION METALS AND AMINO ACIDS |
| title_fullStr | TERNARY COMPLEX FORMATION OF ISONIAZID WITH SOME TRANSITION METALS AND AMINO ACIDS |
| title_full_unstemmed | TERNARY COMPLEX FORMATION OF ISONIAZID WITH SOME TRANSITION METALS AND AMINO ACIDS |
| title_short | TERNARY COMPLEX FORMATION OF ISONIAZID WITH SOME TRANSITION METALS AND AMINO ACIDS |
| title_sort | ternary complex formation of isoniazid with some transition metals and amino acids |
| topic | : i̇soniazid l-asparajin l-glutamik asit metal kompleks potansiyometri kararlılık sabiti isoniazid l-asparagine l-glutamic acid metal complex satibility constant |
| url | https://dergipark.org.tr/en/download/article-file/234510 |
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