Matrix metalloproteinase-9 as an independent predictor of recurrence after catheter ablation of atrial fibrillation
Objectives: In this study, the serum level of matrix metalloproteinase-9 was studied as an independent predictor of recurrence after catheter ablation of a persistent form of atrial fibrillation. Methods: The study included 46 patients with a persistent form of atrial fibrillation. In all patients,...
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2017-05-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/24359 |
| _version_ | 1818266493063790592 |
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| author | A. V. Goryachiy A. I. Gozhenko E. M. Levchenko V. V. Goriachyi M. A. Kuznetsova M. I. Arapu |
| author_facet | A. V. Goryachiy A. I. Gozhenko E. M. Levchenko V. V. Goriachyi M. A. Kuznetsova M. I. Arapu |
| author_sort | A. V. Goryachiy |
| collection | DOAJ |
| description | Objectives: In this study, the serum level of matrix metalloproteinase-9 was studied as an independent predictor of recurrence after catheter ablation of a persistent form of atrial fibrillation.
Methods: The study included 46 patients with a persistent form of atrial fibrillation. In all patients, serum level of matrix metalloproteinase-9 was measured before the procedure of catheter radiofrequency ablation and its association with recurrence of arrhythmia at the end of the postoperative period was estimated.
Results: The follow-up period was 12.3+ for 6.4 months, in 16 (34.7%) patients there was a relapse of arrhythmia after the procedure of catheter radiofrequency ablation. The baseline level of matrix metalloproteinase-9 was higher in patients with relapsed arrhythmia (297.73 + 81.28 and 234.41 + 93.36 ng / ml, respectively, p=0.006). Multivariate analysis showed that parameters such as the level of matrix metalloproteinase-9, the history of atrial fibrillation and the diameter of the left atrium were independent predictors of arrhythmia recurrence.
Conclusion: The serum level of matrix metalloproteinase-9 is an independent predictor of arrhythmia recurrence after performing the procedure of catheter radiofrequency ablation in patients with persistent form of atrial fibrillation. |
| first_indexed | 2024-12-12T20:07:34Z |
| format | Article |
| id | doaj.art-af49e818790e4fd4ae6784d745de873a |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-12-12T20:07:34Z |
| publishDate | 2017-05-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-af49e818790e4fd4ae6784d745de873a2022-12-22T00:13:36ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062017-05-0175Matrix metalloproteinase-9 as an independent predictor of recurrence after catheter ablation of atrial fibrillationA. V. Goryachiy0A. I. Gozhenko1E. M. Levchenko2V. V. Goriachyi3M. A. Kuznetsova4M. I. Arapu5Odessa Regional Clinical HospitalUkrainian Research Institute of Transport MedicineOdessa Regional Clinical HospitalOdessa Regional Clinical HospitalOdessa Regional Clinical HospitalOdessa Regional Clinical HospitalObjectives: In this study, the serum level of matrix metalloproteinase-9 was studied as an independent predictor of recurrence after catheter ablation of a persistent form of atrial fibrillation. Methods: The study included 46 patients with a persistent form of atrial fibrillation. In all patients, serum level of matrix metalloproteinase-9 was measured before the procedure of catheter radiofrequency ablation and its association with recurrence of arrhythmia at the end of the postoperative period was estimated. Results: The follow-up period was 12.3+ for 6.4 months, in 16 (34.7%) patients there was a relapse of arrhythmia after the procedure of catheter radiofrequency ablation. The baseline level of matrix metalloproteinase-9 was higher in patients with relapsed arrhythmia (297.73 + 81.28 and 234.41 + 93.36 ng / ml, respectively, p=0.006). Multivariate analysis showed that parameters such as the level of matrix metalloproteinase-9, the history of atrial fibrillation and the diameter of the left atrium were independent predictors of arrhythmia recurrence. Conclusion: The serum level of matrix metalloproteinase-9 is an independent predictor of arrhythmia recurrence after performing the procedure of catheter radiofrequency ablation in patients with persistent form of atrial fibrillation.https://apcz.umk.pl/JEHS/article/view/24359matrix metalloproteinase - 9atrial fibrillationcatheter ablation |
| spellingShingle | A. V. Goryachiy A. I. Gozhenko E. M. Levchenko V. V. Goriachyi M. A. Kuznetsova M. I. Arapu Matrix metalloproteinase-9 as an independent predictor of recurrence after catheter ablation of atrial fibrillation Journal of Education, Health and Sport matrix metalloproteinase - 9 atrial fibrillation catheter ablation |
| title | Matrix metalloproteinase-9 as an independent predictor of recurrence after catheter ablation of atrial fibrillation |
| title_full | Matrix metalloproteinase-9 as an independent predictor of recurrence after catheter ablation of atrial fibrillation |
| title_fullStr | Matrix metalloproteinase-9 as an independent predictor of recurrence after catheter ablation of atrial fibrillation |
| title_full_unstemmed | Matrix metalloproteinase-9 as an independent predictor of recurrence after catheter ablation of atrial fibrillation |
| title_short | Matrix metalloproteinase-9 as an independent predictor of recurrence after catheter ablation of atrial fibrillation |
| title_sort | matrix metalloproteinase 9 as an independent predictor of recurrence after catheter ablation of atrial fibrillation |
| topic | matrix metalloproteinase - 9 atrial fibrillation catheter ablation |
| url | https://apcz.umk.pl/JEHS/article/view/24359 |
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