The Effect of Liposuction Cannula Diameter on Fat Retention—Based on a Rheological Simulation
Background:. Autologous fat is considered as an ideal material for soft-tissue augmentation in plastic and reconstructive surgery. The primary drawback of autologous fat grafting is the high absorption rate, thus fat retention is considered as an essential indicator. There are several researches abo...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer
2018-11-01
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| Series: | Plastic and Reconstructive Surgery, Global Open |
| Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002021 |
| _version_ | 1819262739930939392 |
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| author | Yuanren Tong Penghao Liu Yuneng Wang Chang Geng Xuefeng Han, MD, PhD Jiguang Ma, MD Facheng Li, MD, PhD Lei Cai, MD, PhD |
| author_facet | Yuanren Tong Penghao Liu Yuneng Wang Chang Geng Xuefeng Han, MD, PhD Jiguang Ma, MD Facheng Li, MD, PhD Lei Cai, MD, PhD |
| author_sort | Yuanren Tong |
| collection | DOAJ |
| description | Background:. Autologous fat is considered as an ideal material for soft-tissue augmentation in plastic and reconstructive surgery. The primary drawback of autologous fat grafting is the high absorption rate, thus fat retention is considered as an essential indicator. There are several researches about the factors that can influence fat retention, including centrifugation and cannula size. However, rheological models of cannula during liposuction are limited. This research focuses on the effects of cannulas with diameters of 2 mm and 2.5 mm on fat retention, which is based on a rheological simulation of inlet pressure and maximum velocity. Experiments on mice were also conducted to confirm the result from the simulation.
Methods:. A simulation was conducted with the physical parameters of the adipose tissue. Human lipoaspirate samples were obtained from patients by liposuction through cannulas of different diameters and were transferred into subcutaneous tissue of nude mice, a part of which were used in viscosity and density measurement. Graft retention was measured and fat quality was assessed through histologic analysis after 6 months.
Results:. Viscosity and density of the fat tissue had significant effects on fat retention. The 2.5 mm diameter cannula had significantly lower inlet pressure and maximum velocity and thus led to higher graft retention, but oil cystic nodules appeared meanwhile.
Conclusions:. Cannulas with larger diameters have lower inlet pressure and maximum velocity during the liposuction process, which further influences the viability of adipocytes and adipose stem cells and thus has larger fat graft retention. This research built a mathematical model with less bias than in vivo experiments and provides a general way for analyzing the outcome of a liposuction precisely, which adds to the data for cannula optimization. |
| first_indexed | 2024-12-23T20:02:29Z |
| format | Article |
| id | doaj.art-af4ad82cb3f345e7bd0a55af17ff2409 |
| institution | Directory Open Access Journal |
| issn | 2169-7574 |
| language | English |
| last_indexed | 2024-12-23T20:02:29Z |
| publishDate | 2018-11-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Plastic and Reconstructive Surgery, Global Open |
| spelling | doaj.art-af4ad82cb3f345e7bd0a55af17ff24092022-12-21T17:33:03ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742018-11-01611e202110.1097/GOX.0000000000002021201811000-00021The Effect of Liposuction Cannula Diameter on Fat Retention—Based on a Rheological SimulationYuanren Tong0Penghao Liu1Yuneng Wang2Chang Geng3Xuefeng Han, MD, PhD4Jiguang Ma, MD5Facheng Li, MD, PhD6Lei Cai, MD, PhD7From the *Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, ChinaFrom the *Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China†Department of Body Contouring and Fat Grafting Center of Plastic Surgery Hospital of Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, ChinaFrom the *Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China†Department of Body Contouring and Fat Grafting Center of Plastic Surgery Hospital of Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China‡Department of Aesthetic Face and Neck Plastic Surgery Center of Plastic Surgery Hospital of Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.†Department of Body Contouring and Fat Grafting Center of Plastic Surgery Hospital of Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China†Department of Body Contouring and Fat Grafting Center of Plastic Surgery Hospital of Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, ChinaBackground:. Autologous fat is considered as an ideal material for soft-tissue augmentation in plastic and reconstructive surgery. The primary drawback of autologous fat grafting is the high absorption rate, thus fat retention is considered as an essential indicator. There are several researches about the factors that can influence fat retention, including centrifugation and cannula size. However, rheological models of cannula during liposuction are limited. This research focuses on the effects of cannulas with diameters of 2 mm and 2.5 mm on fat retention, which is based on a rheological simulation of inlet pressure and maximum velocity. Experiments on mice were also conducted to confirm the result from the simulation. Methods:. A simulation was conducted with the physical parameters of the adipose tissue. Human lipoaspirate samples were obtained from patients by liposuction through cannulas of different diameters and were transferred into subcutaneous tissue of nude mice, a part of which were used in viscosity and density measurement. Graft retention was measured and fat quality was assessed through histologic analysis after 6 months. Results:. Viscosity and density of the fat tissue had significant effects on fat retention. The 2.5 mm diameter cannula had significantly lower inlet pressure and maximum velocity and thus led to higher graft retention, but oil cystic nodules appeared meanwhile. Conclusions:. Cannulas with larger diameters have lower inlet pressure and maximum velocity during the liposuction process, which further influences the viability of adipocytes and adipose stem cells and thus has larger fat graft retention. This research built a mathematical model with less bias than in vivo experiments and provides a general way for analyzing the outcome of a liposuction precisely, which adds to the data for cannula optimization.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002021 |
| spellingShingle | Yuanren Tong Penghao Liu Yuneng Wang Chang Geng Xuefeng Han, MD, PhD Jiguang Ma, MD Facheng Li, MD, PhD Lei Cai, MD, PhD The Effect of Liposuction Cannula Diameter on Fat Retention—Based on a Rheological Simulation Plastic and Reconstructive Surgery, Global Open |
| title | The Effect of Liposuction Cannula Diameter on Fat Retention—Based on a Rheological Simulation |
| title_full | The Effect of Liposuction Cannula Diameter on Fat Retention—Based on a Rheological Simulation |
| title_fullStr | The Effect of Liposuction Cannula Diameter on Fat Retention—Based on a Rheological Simulation |
| title_full_unstemmed | The Effect of Liposuction Cannula Diameter on Fat Retention—Based on a Rheological Simulation |
| title_short | The Effect of Liposuction Cannula Diameter on Fat Retention—Based on a Rheological Simulation |
| title_sort | effect of liposuction cannula diameter on fat retention based on a rheological simulation |
| url | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002021 |
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