Intervention time decides the status of autophagy, NLRP3 activity and apoptosis in macrophages induced by ox‐LDL

Intervention time decides the status of autophagy, NLRP3 activity and apoptosis in macrophages induced by ox‐LDL

Abstract Background It has been determined through extensive studies that autophagy, the Nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome and apoptotic responses in macrophages jointly contribute to atherogenesis and its development in the presen...

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Bibliographic Details
Main Authors: Liang Zheng, Hongbiao Xu, Fufu Zheng, Yuanhui Lai, Jie Li, Weiming Lv, Zuojun Hu, Wenjian Wang
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Lipids in Health and Disease
Subjects:
Atherosclerosis
Autophagy
Nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3
Apoptosis; oxidized low-density lipoprotein
Macrophage
Online Access:https://doi.org/10.1186/s12944-022-01714-x

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