O papel das proteínas reguladoras do complemento CD55/CD59 em células de sangue periférico de pacientes com lúpus eritematoso sistêmico The role of CD55/CD59 complement regulatory proteins on peripheral blood cells of systemic lupus erythematosus patients

O papel das proteínas reguladoras do complemento CD55/CD59 em células de sangue periférico de pacientes com lúpus eritematoso sistêmico The role of CD55/CD59 complement regulatory proteins on peripheral blood cells of systemic lupus erythematosus patients

CD55 e CD59 são proteínas de membrana ancoradas por glicosilfosfatidilinositol que apresentam propriedades reguladoras da ativação da cascata do complemento. Essa regulação ocorre através da inibição da C3 convertase pelo CD55 e prevenção da etapa final de polimerização do complexo de ataque à membr...

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Bibliographic Details
Main Authors:	Ana Paula Alegretti, Tamara Mucenic, João Carlos Tavares Brenol, Ricardo Machado Xavier
Format:	Article
Language:	English
Published:	Sociedade Brasileira de Reumatologia 2009-06-01
Series:	Revista Brasileira de Reumatologia
Subjects:	lúpus eritematoso sistêmico (LES) CD55 CD59 complemento systemic lupus erythematosus (SLE) complement
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042009000300009

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