Untargeted Metabolomics by Ultra-High-Performance Liquid Chromatography Coupled with Electrospray Ionization-Quadrupole-Time of Flight-Mass Spectrometry Analysis Identifies a Specific Metabolomic Profile in Patients with Early Chronic Kidney Disease

Untargeted Metabolomics by Ultra-High-Performance Liquid Chromatography Coupled with Electrospray Ionization-Quadrupole-Time of Flight-Mass Spectrometry Analysis Identifies a Specific Metabolomic Profile in Patients with Early Chronic Kidney Disease

Chronic kidney disease (CKD) has emerged as one of the most progressive diseases with increased mortality and morbidity. Metabolomics offers new insights into CKD pathogenesis and the discovery of new biomarkers for the early diagnosis of CKD. The aim of this cross-sectional study was to assess meta...

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Bibliographic Details
Main Authors: Mihaela-Roxana Glavan, Carmen Socaciu, Andreea Iulia Socaciu, Florica Gadalean, Octavian M. Cretu, Adrian Vlad, Danina M. Muntean, Flaviu Bob, Oana Milas, Anca Suteanu, Dragos Catalin Jianu, Maria Stefan, Lavinia Balint, Silvia Ienciu, Ligia Petrica
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomedicines
Subjects:
chronic kidney disease
metabolomics
biomarkers
amino acids
uremic toxins
acylcarnitines
Online Access:https://www.mdpi.com/2227-9059/11/4/1057

Internet

https://www.mdpi.com/2227-9059/11/4/1057

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