Prevalence of diabetes and pre-diabetes in Sri Lanka: a new global hotspot–estimates from the Sri Lanka Health and Ageing Survey 2018/2019
Introduction This study’s objective was to produce robust, comparable estimates of the prevalence of diabetes and pre-diabetes in the Sri Lankan adult population, where previous studies suggest the highest prevalence in South Asia.Research design and methods We used data on 6661 adults from the nati...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2023-02-01
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| Series: | BMJ Open Diabetes Research & Care |
| Online Access: | https://drc.bmj.com/content/11/1/e003160.full |
| _version_ | 1797901546716921856 |
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| author | Renuka Jayatissa Sarath Samarage Ravindra Prasan Rannan-Eliya Nilmini Wijemunige Prasadini Perera Yasodhara Kapuge Nishani Gunawardana Chathurani Sigera H M M Herath Anuji Gamage Nethmi Weerawardena Ishwari Sivagnanam Shanti Dalpatadu Upeka Samarakoon Navami Samaranayake Cheroni Pullenayegam Bilesha Perera Vajira Dissanayake |
| author_facet | Renuka Jayatissa Sarath Samarage Ravindra Prasan Rannan-Eliya Nilmini Wijemunige Prasadini Perera Yasodhara Kapuge Nishani Gunawardana Chathurani Sigera H M M Herath Anuji Gamage Nethmi Weerawardena Ishwari Sivagnanam Shanti Dalpatadu Upeka Samarakoon Navami Samaranayake Cheroni Pullenayegam Bilesha Perera Vajira Dissanayake |
| collection | DOAJ |
| description | Introduction This study’s objective was to produce robust, comparable estimates of the prevalence of diabetes and pre-diabetes in the Sri Lankan adult population, where previous studies suggest the highest prevalence in South Asia.Research design and methods We used data on 6661 adults from the nationally representative 2018/2019 first wave of the Sri Lanka Health and Ageing Study (SLHAS). We classified glycemic status based on previous diabetes diagnosis, and either fasting plasma glucose (FPG), or FPG and 2-hour plasma glucose (2-h PG). We estimated crude and age-standardized prevalence of pre-diabetes and diabetes and by major individual characteristics weighting the data to account for study design and subject participation.Results Crude prevalence of diabetes in adults was 23.0% (95% CI 21.2% to 24.7%) using both 2-h PG and FPG, and age-standardized prevalence was 21.8% (95% CI 20.1% to 23.5%). Using only FPG, prevalence was 18.5% (95% CI 7.1% to 19.8%). Previously diagnosed prevalence was 14.3% (95% CI 13.1% to 15.5%) of all adults. The prevalence of pre-diabetes was 30.5% (95% CI 28.2% to 32.7%). Diabetes prevalence increased with age until ages ≥70 years and was more prevalent in female, urban, more affluent, and Muslim adults. Diabetes and pre-diabetes prevalence increased with body mass index (BMI) but was as high as 21% and 29%, respectively, in those of normal weight.Conclusions Study limitations included using only a single visit to assess diabetes, relying on self-reported fasting times, and unavailability of glycated hemoglobin for most participants. Our results indicate that Sri Lanka has a very high diabetes prevalence, significantly higher than previous estimates of 8%–15% and higher than current global estimates for any other Asian country. Our results have implications for other populations of South Asian origin, and the high prevalence of diabetes and dysglycemia at normal body weight indicates the need for further research to understand the underlying drivers. |
| first_indexed | 2024-04-10T09:03:37Z |
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| id | doaj.art-af52153496f649c9b2b331f12877682c |
| institution | Directory Open Access Journal |
| issn | 2052-4897 |
| language | English |
| last_indexed | 2024-04-10T09:03:37Z |
| publishDate | 2023-02-01 |
| publisher | BMJ Publishing Group |
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| series | BMJ Open Diabetes Research & Care |
| spelling | doaj.art-af52153496f649c9b2b331f12877682c2023-02-21T09:30:13ZengBMJ Publishing GroupBMJ Open Diabetes Research & Care2052-48972023-02-0111110.1136/bmjdrc-2022-003160Prevalence of diabetes and pre-diabetes in Sri Lanka: a new global hotspot–estimates from the Sri Lanka Health and Ageing Survey 2018/2019 Renuka Jayatissa0Sarath Samarage1Ravindra Prasan Rannan-Eliya2Nilmini Wijemunige3Prasadini Perera4Yasodhara Kapuge5Nishani Gunawardana6Chathurani Sigera7H M M Herath8Anuji Gamage9Nethmi Weerawardena10Ishwari Sivagnanam11Shanti Dalpatadu12Upeka Samarakoon13Navami Samaranayake14Cheroni Pullenayegam15Bilesha Perera16Vajira DissanayakeMedical Research Institute, Ministry of Health, Colombo, Sri LankaInstitute for Health Policy, Colombo, Sri LankaInstitute for Health Policy, Colombo, Sri LankaInstitute for Health Policy, Colombo, Sri LankaFaculty of Allied Health Sciences, University of Peradeniya, Peradeniya, Sri LankaInstitute for Health Policy, Colombo, Sri LankaInstitute for Health Policy, Colombo, Sri LankaFaculty of Medicine, University of Colombo, Colombo, Sri LankaFaculty of Medicine, University of Ruhuna, Galle, Sri LankaFaculty of Medicine, General Sir John Kotelawala Defence University, Rathmalana, Sri LankaInstitute for Health Policy, Colombo, Sri LankaInstitute for Health Policy, Colombo, Sri LankaInstitute for Health Policy, Colombo, Sri LankaInstitute for Health Policy, Colombo, Sri LankaMinistry of Health, Colombo, Sri LankaInstitute for Health Policy, Colombo, Sri LankaFaculty of Medicine, University of Ruhuna, Galle, Sri LankaIntroduction This study’s objective was to produce robust, comparable estimates of the prevalence of diabetes and pre-diabetes in the Sri Lankan adult population, where previous studies suggest the highest prevalence in South Asia.Research design and methods We used data on 6661 adults from the nationally representative 2018/2019 first wave of the Sri Lanka Health and Ageing Study (SLHAS). We classified glycemic status based on previous diabetes diagnosis, and either fasting plasma glucose (FPG), or FPG and 2-hour plasma glucose (2-h PG). We estimated crude and age-standardized prevalence of pre-diabetes and diabetes and by major individual characteristics weighting the data to account for study design and subject participation.Results Crude prevalence of diabetes in adults was 23.0% (95% CI 21.2% to 24.7%) using both 2-h PG and FPG, and age-standardized prevalence was 21.8% (95% CI 20.1% to 23.5%). Using only FPG, prevalence was 18.5% (95% CI 7.1% to 19.8%). Previously diagnosed prevalence was 14.3% (95% CI 13.1% to 15.5%) of all adults. The prevalence of pre-diabetes was 30.5% (95% CI 28.2% to 32.7%). Diabetes prevalence increased with age until ages ≥70 years and was more prevalent in female, urban, more affluent, and Muslim adults. Diabetes and pre-diabetes prevalence increased with body mass index (BMI) but was as high as 21% and 29%, respectively, in those of normal weight.Conclusions Study limitations included using only a single visit to assess diabetes, relying on self-reported fasting times, and unavailability of glycated hemoglobin for most participants. Our results indicate that Sri Lanka has a very high diabetes prevalence, significantly higher than previous estimates of 8%–15% and higher than current global estimates for any other Asian country. Our results have implications for other populations of South Asian origin, and the high prevalence of diabetes and dysglycemia at normal body weight indicates the need for further research to understand the underlying drivers.https://drc.bmj.com/content/11/1/e003160.full |
| spellingShingle | Renuka Jayatissa Sarath Samarage Ravindra Prasan Rannan-Eliya Nilmini Wijemunige Prasadini Perera Yasodhara Kapuge Nishani Gunawardana Chathurani Sigera H M M Herath Anuji Gamage Nethmi Weerawardena Ishwari Sivagnanam Shanti Dalpatadu Upeka Samarakoon Navami Samaranayake Cheroni Pullenayegam Bilesha Perera Vajira Dissanayake Prevalence of diabetes and pre-diabetes in Sri Lanka: a new global hotspot–estimates from the Sri Lanka Health and Ageing Survey 2018/2019 BMJ Open Diabetes Research & Care |
| title | Prevalence of diabetes and pre-diabetes in Sri Lanka: a new global hotspot–estimates from the Sri Lanka Health and Ageing Survey 2018/2019 |
| title_full | Prevalence of diabetes and pre-diabetes in Sri Lanka: a new global hotspot–estimates from the Sri Lanka Health and Ageing Survey 2018/2019 |
| title_fullStr | Prevalence of diabetes and pre-diabetes in Sri Lanka: a new global hotspot–estimates from the Sri Lanka Health and Ageing Survey 2018/2019 |
| title_full_unstemmed | Prevalence of diabetes and pre-diabetes in Sri Lanka: a new global hotspot–estimates from the Sri Lanka Health and Ageing Survey 2018/2019 |
| title_short | Prevalence of diabetes and pre-diabetes in Sri Lanka: a new global hotspot–estimates from the Sri Lanka Health and Ageing Survey 2018/2019 |
| title_sort | prevalence of diabetes and pre diabetes in sri lanka a new global hotspot estimates from the sri lanka health and ageing survey 2018 2019 |
| url | https://drc.bmj.com/content/11/1/e003160.full |
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