Moderately Differentiated Neuroendocrine Carcinoma of the Larynx
Neuroendocrine neoplasm of the larynx is a morphologically heterogeneous group of tumors. This unusual neoplasm includes the four different type of tumors. Paraganglioma is the best-known neural origin tumor. The epithelial origin tumor is further divided based on the degree of differentiation into...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Korean Society of Otorhinolaryngology-Head and Neck Surgery
2008-12-01
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| Series: | Clinical and Experimental Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://www.e-ceo.org/upload/pdf/ceo-1-217.pdf |
| _version_ | 1818586976011419648 |
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| author | Eun-Jae Chung Seung-Kuk Baek Soon-Young Kwon Jung-Soo Woo Kwang-Yoon Jung |
| author_facet | Eun-Jae Chung Seung-Kuk Baek Soon-Young Kwon Jung-Soo Woo Kwang-Yoon Jung |
| author_sort | Eun-Jae Chung |
| collection | DOAJ |
| description | Neuroendocrine neoplasm of the larynx is a morphologically heterogeneous group of tumors. This unusual neoplasm includes the four different type of tumors. Paraganglioma is the best-known neural origin tumor. The epithelial origin tumor is further divided based on the degree of differentiation into well, moderately, and poorly differentiated carcinoma. The diverse biological behavior of neuroendocrine neoplasm of larynx makes an accurate diagnosis of paramount importance, since treatment depends on diagnostic accuracy. The diagnosis is based primarily on light microscopy, and immunohistochemical and/or ultrastructural investigations are needed to diagnose correctly. The mainstay of treatment of moderately differentiated neuroendocrine carcinoma of the larynx is surgery. Elective neck treatment should be performed considering the high likelihood of cervical lymph node metastases. The 5-yr survival rate approximates 50%, and 10-yr survival rate is only 30%. |
| first_indexed | 2024-12-16T09:01:31Z |
| format | Article |
| id | doaj.art-af54a764166f48a7983f902f0a4b0030 |
| institution | Directory Open Access Journal |
| issn | 1976-8710 2005-0720 |
| language | English |
| last_indexed | 2024-12-16T09:01:31Z |
| publishDate | 2008-12-01 |
| publisher | Korean Society of Otorhinolaryngology-Head and Neck Surgery |
| record_format | Article |
| series | Clinical and Experimental Otorhinolaryngology |
| spelling | doaj.art-af54a764166f48a7983f902f0a4b00302022-12-21T22:37:09ZengKorean Society of Otorhinolaryngology-Head and Neck SurgeryClinical and Experimental Otorhinolaryngology1976-87102005-07202008-12-011421722010.3342/ceo.2008.1.4.21725Moderately Differentiated Neuroendocrine Carcinoma of the LarynxEun-Jae Chung0Seung-Kuk Baek1Soon-Young Kwon2Jung-Soo Woo3Kwang-Yoon Jung4Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.Neuroendocrine neoplasm of the larynx is a morphologically heterogeneous group of tumors. This unusual neoplasm includes the four different type of tumors. Paraganglioma is the best-known neural origin tumor. The epithelial origin tumor is further divided based on the degree of differentiation into well, moderately, and poorly differentiated carcinoma. The diverse biological behavior of neuroendocrine neoplasm of larynx makes an accurate diagnosis of paramount importance, since treatment depends on diagnostic accuracy. The diagnosis is based primarily on light microscopy, and immunohistochemical and/or ultrastructural investigations are needed to diagnose correctly. The mainstay of treatment of moderately differentiated neuroendocrine carcinoma of the larynx is surgery. Elective neck treatment should be performed considering the high likelihood of cervical lymph node metastases. The 5-yr survival rate approximates 50%, and 10-yr survival rate is only 30%.http://www.e-ceo.org/upload/pdf/ceo-1-217.pdfNeuroendocrine carcinoma |
| spellingShingle | Eun-Jae Chung Seung-Kuk Baek Soon-Young Kwon Jung-Soo Woo Kwang-Yoon Jung Moderately Differentiated Neuroendocrine Carcinoma of the Larynx Clinical and Experimental Otorhinolaryngology Neuroendocrine carcinoma |
| title | Moderately Differentiated Neuroendocrine Carcinoma of the Larynx |
| title_full | Moderately Differentiated Neuroendocrine Carcinoma of the Larynx |
| title_fullStr | Moderately Differentiated Neuroendocrine Carcinoma of the Larynx |
| title_full_unstemmed | Moderately Differentiated Neuroendocrine Carcinoma of the Larynx |
| title_short | Moderately Differentiated Neuroendocrine Carcinoma of the Larynx |
| title_sort | moderately differentiated neuroendocrine carcinoma of the larynx |
| topic | Neuroendocrine carcinoma |
| url | http://www.e-ceo.org/upload/pdf/ceo-1-217.pdf |
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