Choice of pharmacotherapy for various clinical forms of dry eye disease
Purpose: to investigate therapeutic effectiveness of several new pharmacotherapeutic agents for dry eye disease (DED) of various severity and ethiological factors.Methods: there were 72 patients under observation with dry eye disease divided into three groups. Group I-DED mild stage 1, Group II-DED...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Ophthalmology Publishing Group
2014-07-01
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| Series: | Oftalʹmologiâ |
| Subjects: | |
| Online Access: | https://www.ophthalmojournal.com/opht/article/view/177 |
| _version_ | 1797875537020977152 |
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| author | Yu. F. Maychuk E. V. Yani |
| author_facet | Yu. F. Maychuk E. V. Yani |
| author_sort | Yu. F. Maychuk |
| collection | DOAJ |
| description | Purpose: to investigate therapeutic effectiveness of several new pharmacotherapeutic agents for dry eye disease (DED) of various severity and ethiological factors.Methods: there were 72 patients under observation with dry eye disease divided into three groups. Group I-DED mild stage 1, Group II-DED stage 2, moderate stage with secondary damage after adenoviral eye infection. Group III-DED, stage 3, severe damage associated with meibomian gland dysfunction. Diagnostics — subjective symptoms, biomicroscopic data and diagnostic tests were assessed and scored: Schirmer test, Norn test, rose bengal and fluorescein staining, OCt assessment of tear meniscus, tear osmolar- ity measurement. the following agents were used as basis therapy in various algorithms: Visine Pure tears or Artificial tear, Hilabak, VitA-Pos and adjunctive anti-infective and anti-inflammatory therapies if needed.Results: Positive therapeutic effect was achieved in all patients. Subjective symptoms and diagnostic test results improved from the first day.Conclusion: Clinical signs improvement and positive trends in diagnostic test results were seen in all of the three groups of variousseverity and ethiology. there was an effort put in every group to personalize pharmacotherapies. |
| first_indexed | 2024-04-10T01:49:05Z |
| format | Article |
| id | doaj.art-af5bd721be7d4a408fdc9c81d6ded741 |
| institution | Directory Open Access Journal |
| issn | 1816-5095 2500-0845 |
| language | Russian |
| last_indexed | 2024-04-10T01:49:05Z |
| publishDate | 2014-07-01 |
| publisher | Ophthalmology Publishing Group |
| record_format | Article |
| series | Oftalʹmologiâ |
| spelling | doaj.art-af5bd721be7d4a408fdc9c81d6ded7412023-03-13T09:08:35ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452014-07-0194586410.18008/1816-5095-2012-4-58-64177Choice of pharmacotherapy for various clinical forms of dry eye diseaseYu. F. Maychuk0E. V. Yani1ФГУ «Московский НИИ глазных болезней им. Гельмгольца, Минздравсоцразвития России», МоскваФГУ «Московский НИИ глазных болезней им. Гельмгольца, Минздравсоцразвития России», 105062 Москва, ул. Садовая-Черногрязская 14/19Purpose: to investigate therapeutic effectiveness of several new pharmacotherapeutic agents for dry eye disease (DED) of various severity and ethiological factors.Methods: there were 72 patients under observation with dry eye disease divided into three groups. Group I-DED mild stage 1, Group II-DED stage 2, moderate stage with secondary damage after adenoviral eye infection. Group III-DED, stage 3, severe damage associated with meibomian gland dysfunction. Diagnostics — subjective symptoms, biomicroscopic data and diagnostic tests were assessed and scored: Schirmer test, Norn test, rose bengal and fluorescein staining, OCt assessment of tear meniscus, tear osmolar- ity measurement. the following agents were used as basis therapy in various algorithms: Visine Pure tears or Artificial tear, Hilabak, VitA-Pos and adjunctive anti-infective and anti-inflammatory therapies if needed.Results: Positive therapeutic effect was achieved in all patients. Subjective symptoms and diagnostic test results improved from the first day.Conclusion: Clinical signs improvement and positive trends in diagnostic test results were seen in all of the three groups of variousseverity and ethiology. there was an effort put in every group to personalize pharmacotherapies.https://www.ophthalmojournal.com/opht/article/view/177болезнь сухого глазадиагностические тесты сухого глазаслёзозаместительная терапия |
| spellingShingle | Yu. F. Maychuk E. V. Yani Choice of pharmacotherapy for various clinical forms of dry eye disease Oftalʹmologiâ болезнь сухого глаза диагностические тесты сухого глаза слёзозаместительная терапия |
| title | Choice of pharmacotherapy for various clinical forms of dry eye disease |
| title_full | Choice of pharmacotherapy for various clinical forms of dry eye disease |
| title_fullStr | Choice of pharmacotherapy for various clinical forms of dry eye disease |
| title_full_unstemmed | Choice of pharmacotherapy for various clinical forms of dry eye disease |
| title_short | Choice of pharmacotherapy for various clinical forms of dry eye disease |
| title_sort | choice of pharmacotherapy for various clinical forms of dry eye disease |
| topic | болезнь сухого глаза диагностические тесты сухого глаза слёзозаместительная терапия |
| url | https://www.ophthalmojournal.com/opht/article/view/177 |
| work_keys_str_mv | AT yufmaychuk choiceofpharmacotherapyforvariousclinicalformsofdryeyedisease AT evyani choiceofpharmacotherapyforvariousclinicalformsofdryeyedisease |