The effect on intracytoplasmic sperm injection outcome of genotype, male germ cell stage and freeze-thawing in mice.
BACKGROUND: Intracytoplasmic sperm injection (ICSI) has been widely used to study the mechanisms of mammalian fertilization and to rescue male-factor infertility in humans and animals. However, very few systematic analyses have been conducted to define factors affecting the efficiency of ICSI. In th...
Main Authors: | Narumi Ogonuki, Manami Mori, Akie Shinmen, Kimiko Inoue, Keiji Mochida, Akihiko Ohta, Atsuo Ogura |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2884038?pdf=render |
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