The Prevalence of Transfusion Transmitted Infections among Blood Donors in Pakistan: A Retrospective Study
Objectives: This study aimed to determine the prevalence of blood transfusion-transmitted infections (TTIs), among blood donors in Pakistan, specifically HIV, hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis, and malaria. Methods: Data records of all registered blood donors (n = 120 968) d...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Oman Medical Specialty Board
2022-05-01
|
| Series: | Oman Medical Journal |
| Subjects: | |
| Online Access: | https://omjournal.org/articleDetails.aspx?coType=1&aId=3136 |
| _version_ | 1818207338485514240 |
|---|---|
| author | Mahwish Majid Bhatti Ayesha Junaid Fouzia Sadiq |
| author_facet | Mahwish Majid Bhatti Ayesha Junaid Fouzia Sadiq |
| author_sort | Mahwish Majid Bhatti |
| collection | DOAJ |
| description | Objectives: This study aimed to determine the prevalence of blood transfusion-transmitted infections (TTIs), among blood donors in Pakistan, specifically HIV, hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis, and malaria. Methods: Data records of all registered blood donors (n = 120 968) during 2008–2019, at a blood transfusion center in a tertiary care hospital were assessed. Frequency of the seropositive donors for HIV, HCV, HBV, syphilis, and malaria was analyzed. Results: The overall age range of the donors was 25–65 years. Nearly all were male (99.0%). HCV, syphilis, and malaria were more prevalent among those aged 26–35 years. Most donors (81.1%) were residents of Islamabad city. The infection with the highest prevalence among the screened blood donors was HCV (1.5%; 95% CI: 0.423–0.661) followed by syphilis (0.8%; 95% CI: 1.149–1.432). HCV and syphilis were most frequently observed in blood group B positive (B+) donors while HIV was more common in those who were O+. The frequency of co-infection of syphilis with HCV and HIV was 0.02% and 0.01%, respectively. Conclusions: Among male blood donors, the most prevalent TTI infection was HCV followed by HIV; the latter is on the rise. HCV and syphilis are the most frequent co-infections. |
| first_indexed | 2024-12-12T04:27:20Z |
| format | Article |
| id | doaj.art-af5e54c67d4d4a3e8061db0d9672055b |
| institution | Directory Open Access Journal |
| issn | 1999-768X 2070-5204 |
| language | English |
| last_indexed | 2024-12-12T04:27:20Z |
| publishDate | 2022-05-01 |
| publisher | Oman Medical Specialty Board |
| record_format | Article |
| series | Oman Medical Journal |
| spelling | doaj.art-af5e54c67d4d4a3e8061db0d9672055b2022-12-22T00:38:11ZengOman Medical Specialty BoardOman Medical Journal1999-768X2070-52042022-05-01373e386e38610.5001/omj.2022.65The Prevalence of Transfusion Transmitted Infections among Blood Donors in Pakistan: A Retrospective StudyMahwish Majid Bhatti0Ayesha Junaid1Fouzia Sadiq2Department of Pathology, Shifa College of Medicine, Shifa Tameer-e-Millat University, Islamabad, Pakistan; Department of Pathology, Shifa International Hospital, Islamabad, PakistanDepartment of Pathology, Shifa College of Medicine, Shifa Tameer-e-Millat University, Islamabad, Pakistan; Department of Pathology, Shifa International Hospital, Islamabad, PakistanDirectorate of Research, Shifa Tameer-e-Millat University, Islamabad, PakistanObjectives: This study aimed to determine the prevalence of blood transfusion-transmitted infections (TTIs), among blood donors in Pakistan, specifically HIV, hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis, and malaria. Methods: Data records of all registered blood donors (n = 120 968) during 2008–2019, at a blood transfusion center in a tertiary care hospital were assessed. Frequency of the seropositive donors for HIV, HCV, HBV, syphilis, and malaria was analyzed. Results: The overall age range of the donors was 25–65 years. Nearly all were male (99.0%). HCV, syphilis, and malaria were more prevalent among those aged 26–35 years. Most donors (81.1%) were residents of Islamabad city. The infection with the highest prevalence among the screened blood donors was HCV (1.5%; 95% CI: 0.423–0.661) followed by syphilis (0.8%; 95% CI: 1.149–1.432). HCV and syphilis were most frequently observed in blood group B positive (B+) donors while HIV was more common in those who were O+. The frequency of co-infection of syphilis with HCV and HIV was 0.02% and 0.01%, respectively. Conclusions: Among male blood donors, the most prevalent TTI infection was HCV followed by HIV; the latter is on the rise. HCV and syphilis are the most frequent co-infections.https://omjournal.org/articleDetails.aspx?coType=1&aId=3136blood transfusionblood-borne infectionshepatitismalariahivblood donorsblood safetypakistan |
| spellingShingle | Mahwish Majid Bhatti Ayesha Junaid Fouzia Sadiq The Prevalence of Transfusion Transmitted Infections among Blood Donors in Pakistan: A Retrospective Study Oman Medical Journal blood transfusion blood-borne infections hepatitis malaria hiv blood donors blood safety pakistan |
| title | The Prevalence of Transfusion Transmitted Infections among Blood Donors in Pakistan: A Retrospective Study |
| title_full | The Prevalence of Transfusion Transmitted Infections among Blood Donors in Pakistan: A Retrospective Study |
| title_fullStr | The Prevalence of Transfusion Transmitted Infections among Blood Donors in Pakistan: A Retrospective Study |
| title_full_unstemmed | The Prevalence of Transfusion Transmitted Infections among Blood Donors in Pakistan: A Retrospective Study |
| title_short | The Prevalence of Transfusion Transmitted Infections among Blood Donors in Pakistan: A Retrospective Study |
| title_sort | prevalence of transfusion transmitted infections among blood donors in pakistan a retrospective study |
| topic | blood transfusion blood-borne infections hepatitis malaria hiv blood donors blood safety pakistan |
| url | https://omjournal.org/articleDetails.aspx?coType=1&aId=3136 |
| work_keys_str_mv | AT mahwishmajidbhatti theprevalenceoftransfusiontransmittedinfectionsamongblooddonorsinpakistanaretrospectivestudy AT ayeshajunaid theprevalenceoftransfusiontransmittedinfectionsamongblooddonorsinpakistanaretrospectivestudy AT fouziasadiq theprevalenceoftransfusiontransmittedinfectionsamongblooddonorsinpakistanaretrospectivestudy AT mahwishmajidbhatti prevalenceoftransfusiontransmittedinfectionsamongblooddonorsinpakistanaretrospectivestudy AT ayeshajunaid prevalenceoftransfusiontransmittedinfectionsamongblooddonorsinpakistanaretrospectivestudy AT fouziasadiq prevalenceoftransfusiontransmittedinfectionsamongblooddonorsinpakistanaretrospectivestudy |