Quercetin Inhibits Lef1 and Resensitizes Docetaxel-Resistant Breast Cancer Cells

Quercetin Inhibits Lef1 and Resensitizes Docetaxel-Resistant Breast Cancer Cells

Drug resistance is a major problem for breast cancer patients. Docetaxel is an anti-mitotic agent that serves as first line of treatment in metastatic breast cancer, however it is susceptible to cellular drug resistance. Drug-resistant cells are able to spread during treatment, leading to treatment...

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Bibliographic Details
Main Authors: Marta Prieto-Vila, Iwao Shimomura, Akiko Kogure, Wataru Usuba, Ryou-u Takahashi, Takahiro Ochiya, Yusuke Yamamoto
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
quercetin
drug resistance
Lef1
breast cancer
Online Access:https://www.mdpi.com/1420-3049/25/11/2576

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