Impact on mental health, disease management, and socioeconomic modifications in hematological patients during the COVID-19 pandemic in Italy
Background: Hematological patients are a highly vulnerable population with an increased risk of developing severe COVID-19 symptoms due to their immunocompromised status. COVID-19 has proven to cause serious mental health issues, such as stress, anxiety, and depression in the general population. How...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2023-09-01
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| Series: | Therapeutic Advances in Hematology |
| Online Access: | https://doi.org/10.1177/20406207231190683 |
| _version_ | 1797691096048861184 |
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| author | Marianna De Muro Annelot Julia Janssen Sergio Amadori Paolo de Fabritiis Dante Sabatino Pasquale Niscola Lorenza Torti Malgorzata Monika Trawinska Cristiano Tesei Felice Bombaci Mario Tarricone Monica Bocchia Carmen Fava Sara Galimberti Alessandra Iurlo Luigia Luciano Elisabetta Abruzzese |
| author_facet | Marianna De Muro Annelot Julia Janssen Sergio Amadori Paolo de Fabritiis Dante Sabatino Pasquale Niscola Lorenza Torti Malgorzata Monika Trawinska Cristiano Tesei Felice Bombaci Mario Tarricone Monica Bocchia Carmen Fava Sara Galimberti Alessandra Iurlo Luigia Luciano Elisabetta Abruzzese |
| author_sort | Marianna De Muro |
| collection | DOAJ |
| description | Background: Hematological patients are a highly vulnerable population with an increased risk of developing severe COVID-19 symptoms due to their immunocompromised status. COVID-19 has proven to cause serious mental health issues, such as stress, anxiety, and depression in the general population. However, data on the psycho-social impact of COVID-19 on hematological patients are lacking. Objectives: This study aims to examine the psychological well-being of hematological patients in Italy during the initial period of the COVID-19 pandemic. Furthermore, it seeks to explore the association between modifications in the management of hematological diseases and employment status of these patients during the COVID-19 pandemic and the resulting mental health outcomes. Design and Methods: A survey using the DASS-21 questionnaire was administered to 1105 hematological patients. Data analysis was conducted using the R software, and logistic regression analysis was performed to predict the association between hematological patient/general population and employment status with DASS scores. Results: The hematological patient population reported significantly higher levels of depression (OR 0.947, 95% CI 0.966–0.982, p < 0.001), anxiety (OR 0.948, 95% CI 0.939–0.958, p < 0.001), and stress (OR 0.984, 95% CI 0.977–0.992, p < 0.001) compared with the general population. A significant relationship has been found in stress between employed and unemployed patients (OR 1.015, 95% CI 1.000–1.030, p = 0.044), as well as in the control group (OR 1.024, 95% CI 1.010–1.039, p = 0.001). In addition, employment status is significantly related to depression, anxiety, and stress in both the hematological patient group and the general population. Conclusion: During the initial phase of the COVID-19 pandemic, hematological patients had elevated levels of depression, anxiety, and stress compared with the general population. The delay in their treatment and employment status played a role in their mental health outcomes. These findings emphasize the importance of further research to gain deeper insight into the long-term psychological effects and explore effective strategies for managing mental health in similar crises. |
| first_indexed | 2024-03-12T02:08:28Z |
| format | Article |
| id | doaj.art-af627156801d40d49d02c8981f132558 |
| institution | Directory Open Access Journal |
| issn | 2040-6215 |
| language | English |
| last_indexed | 2024-03-12T02:08:28Z |
| publishDate | 2023-09-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Hematology |
| spelling | doaj.art-af627156801d40d49d02c8981f1325582023-09-06T21:04:17ZengSAGE PublishingTherapeutic Advances in Hematology2040-62152023-09-011410.1177/20406207231190683Impact on mental health, disease management, and socioeconomic modifications in hematological patients during the COVID-19 pandemic in ItalyMarianna De MuroAnnelot Julia JanssenSergio AmadoriPaolo de FabritiisDante SabatinoPasquale NiscolaLorenza TortiMalgorzata Monika TrawinskaCristiano TeseiFelice BombaciMario TarriconeMonica BocchiaCarmen FavaSara GalimbertiAlessandra IurloLuigia LucianoElisabetta AbruzzeseBackground: Hematological patients are a highly vulnerable population with an increased risk of developing severe COVID-19 symptoms due to their immunocompromised status. COVID-19 has proven to cause serious mental health issues, such as stress, anxiety, and depression in the general population. However, data on the psycho-social impact of COVID-19 on hematological patients are lacking. Objectives: This study aims to examine the psychological well-being of hematological patients in Italy during the initial period of the COVID-19 pandemic. Furthermore, it seeks to explore the association between modifications in the management of hematological diseases and employment status of these patients during the COVID-19 pandemic and the resulting mental health outcomes. Design and Methods: A survey using the DASS-21 questionnaire was administered to 1105 hematological patients. Data analysis was conducted using the R software, and logistic regression analysis was performed to predict the association between hematological patient/general population and employment status with DASS scores. Results: The hematological patient population reported significantly higher levels of depression (OR 0.947, 95% CI 0.966–0.982, p < 0.001), anxiety (OR 0.948, 95% CI 0.939–0.958, p < 0.001), and stress (OR 0.984, 95% CI 0.977–0.992, p < 0.001) compared with the general population. A significant relationship has been found in stress between employed and unemployed patients (OR 1.015, 95% CI 1.000–1.030, p = 0.044), as well as in the control group (OR 1.024, 95% CI 1.010–1.039, p = 0.001). In addition, employment status is significantly related to depression, anxiety, and stress in both the hematological patient group and the general population. Conclusion: During the initial phase of the COVID-19 pandemic, hematological patients had elevated levels of depression, anxiety, and stress compared with the general population. The delay in their treatment and employment status played a role in their mental health outcomes. These findings emphasize the importance of further research to gain deeper insight into the long-term psychological effects and explore effective strategies for managing mental health in similar crises.https://doi.org/10.1177/20406207231190683 |
| spellingShingle | Marianna De Muro Annelot Julia Janssen Sergio Amadori Paolo de Fabritiis Dante Sabatino Pasquale Niscola Lorenza Torti Malgorzata Monika Trawinska Cristiano Tesei Felice Bombaci Mario Tarricone Monica Bocchia Carmen Fava Sara Galimberti Alessandra Iurlo Luigia Luciano Elisabetta Abruzzese Impact on mental health, disease management, and socioeconomic modifications in hematological patients during the COVID-19 pandemic in Italy Therapeutic Advances in Hematology |
| title | Impact on mental health, disease management, and socioeconomic modifications in hematological patients during the COVID-19 pandemic in Italy |
| title_full | Impact on mental health, disease management, and socioeconomic modifications in hematological patients during the COVID-19 pandemic in Italy |
| title_fullStr | Impact on mental health, disease management, and socioeconomic modifications in hematological patients during the COVID-19 pandemic in Italy |
| title_full_unstemmed | Impact on mental health, disease management, and socioeconomic modifications in hematological patients during the COVID-19 pandemic in Italy |
| title_short | Impact on mental health, disease management, and socioeconomic modifications in hematological patients during the COVID-19 pandemic in Italy |
| title_sort | impact on mental health disease management and socioeconomic modifications in hematological patients during the covid 19 pandemic in italy |
| url | https://doi.org/10.1177/20406207231190683 |
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