Multiple molecular forms of adaptor protein Ruk/CIN85 specifically associate with different subcellular compartments in human breast adenocarcinoma MCF-7 cells

Multiple molecular forms of adaptor protein Ruk/CIN85 specifically associate with different subcellular compartments in human breast adenocarcinoma MCF-7 cells

Ruk/CIN85 is a receptor-proximal ‘signalling’ adaptor that possesses three SH3 domains, Pro- and Ser-rich regions and C-terminal coiled-coil domain. It employs distinct domains and motifs to act as a transducer platform in intracellular signalling. Based on cDNA analysis, various isoforms of Ruk/CIN...

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Bibliographic Details
Main Authors: B. O. Vynnytska-Myronovska, Ya. P. Bobak, G. V. Pasichnyk, N. I. Igumentseva, A. A. Samoylenko, L. B. Drobot
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2014-10-01
Series:The Ukrainian Biochemical Journal
Subjects:
adaptor proteins
apoptosis
MCF-7 cells
multiple molecular forms
Ruk/CIN85
subcellular distribution
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2015/06/Vynnytska-Myronovska_5_14.pdf

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