Foetal Brain Biometry using Magnetic Resonance Imaging in an Indian Population- A Retrospective Cohort Study
Introduction: The utility of Magnetic Resonance Imaging (MRI) has increased significantly in the assessment of foetal brain development. Foetal biometry is a part of every imaging examination and is needed to confirm that the growth is proceeding normally. Aim: To provide normal MRI reference b...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2022-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/16855/56573_CE(AnK)_F[SH]_PF1(SC_SS)_PFA(SC_SS)_PN(SS).pdf |
| _version_ | 1797950619465547776 |
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| author | Chandrasekhar Priyanka Rajeswaran Rangasami Chitra Andrew N Paarthipan |
| author_facet | Chandrasekhar Priyanka Rajeswaran Rangasami Chitra Andrew N Paarthipan |
| author_sort | Chandrasekhar Priyanka |
| collection | DOAJ |
| description | Introduction: The utility of Magnetic Resonance Imaging
(MRI) has increased significantly in the assessment of foetal
brain development. Foetal biometry is a part of every imaging
examination and is needed to confirm that the growth is
proceeding normally.
Aim: To provide normal MRI reference biometric data of the foetal
brain in Indian population.
Materials and Methods: This was a retrospective cohort
study conducted in the Department of Radiodiagnosis at Sri
Ramachandra Hospital, Chennai, Tamil Nadu, India. The data
was collected from the MR imaging studies done between
January 2013 to December 2020. The present study was carried
out on 101 foetuses with gestational age ranging from 20 to
38 gestational weeks with normal brain appearance. Following
biometric parameters had been obtained: skull occipitofrontal
diameter and Biparietal Diameter (BPD), Brain-Biparietal Diameter
(BPD) and fronto-occipital length, Head Circumference (HC), atrial
diameter, vermian height, width and area. Descriptive statistics
was used to calculate the median value with Interquartile Range (IQR). A p-value of less than 0.05 was considered as significant
using Spearman’s rank correlation.
Results: The skull occipitofrontal diameter (r-value=0.88, p-value
<0.001), skull biparietal diameter (r-value=0.92, p-value <0.001),
brain biparietal diameter (r-value=0.95, p-value <0.001), brain
fronto-occipital length (r=0.94, p-value <0.001), head circumference
(r-value=0.92, p-value <0.001), atrial diameter (r-value=0.86,
p-value <0.001), Vermian height (r-value=0.86, p-value <0.001),
Vermian width (r-value=0.84, p-value <0.001) and Vermian area
(r-value=0.88, p-value <0.001) showed positive correlation with
gestational age. Mean Head Circumference (HC) and BPD values
were almost similar to the standard Indian reference mean values
of ultrasound. All biometric parameters were compared with the
European references. The values from present study were found
to be in the lower range of the European biometric values.
Conclusion: Normal biometric MRI data of the foetal brain in
an Indian population from 20 to 38 weeks gestational age was
presented. A significant correlation was found between gestational
age and parameters. MRI BPD and HC values showed a positive
correlation with ultrasound BPD and HC values. |
| first_indexed | 2024-04-10T22:17:53Z |
| format | Article |
| id | doaj.art-af63e28b976547d387b12ab6f43dc8e3 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-10T22:17:53Z |
| publishDate | 2022-10-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-af63e28b976547d387b12ab6f43dc8e32023-01-18T06:54:08ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2022-10-011610TC01TC0410.7860/JCDR/2022/56573.16855Foetal Brain Biometry using Magnetic Resonance Imaging in an Indian Population- A Retrospective Cohort StudyChandrasekhar Priyanka0Rajeswaran Rangasami1Chitra Andrew2N Paarthipan3Ph.D Student, Department of Radiology and Imaging Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.Professor, Department of Radiology and Imaging Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.Professor, Department of Obstetrics and Gynaecology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.Professor, Department of Radiology, Saveetha Medical College and Hospital, Chennai, Tamil Nadu, India.Introduction: The utility of Magnetic Resonance Imaging (MRI) has increased significantly in the assessment of foetal brain development. Foetal biometry is a part of every imaging examination and is needed to confirm that the growth is proceeding normally. Aim: To provide normal MRI reference biometric data of the foetal brain in Indian population. Materials and Methods: This was a retrospective cohort study conducted in the Department of Radiodiagnosis at Sri Ramachandra Hospital, Chennai, Tamil Nadu, India. The data was collected from the MR imaging studies done between January 2013 to December 2020. The present study was carried out on 101 foetuses with gestational age ranging from 20 to 38 gestational weeks with normal brain appearance. Following biometric parameters had been obtained: skull occipitofrontal diameter and Biparietal Diameter (BPD), Brain-Biparietal Diameter (BPD) and fronto-occipital length, Head Circumference (HC), atrial diameter, vermian height, width and area. Descriptive statistics was used to calculate the median value with Interquartile Range (IQR). A p-value of less than 0.05 was considered as significant using Spearman’s rank correlation. Results: The skull occipitofrontal diameter (r-value=0.88, p-value <0.001), skull biparietal diameter (r-value=0.92, p-value <0.001), brain biparietal diameter (r-value=0.95, p-value <0.001), brain fronto-occipital length (r=0.94, p-value <0.001), head circumference (r-value=0.92, p-value <0.001), atrial diameter (r-value=0.86, p-value <0.001), Vermian height (r-value=0.86, p-value <0.001), Vermian width (r-value=0.84, p-value <0.001) and Vermian area (r-value=0.88, p-value <0.001) showed positive correlation with gestational age. Mean Head Circumference (HC) and BPD values were almost similar to the standard Indian reference mean values of ultrasound. All biometric parameters were compared with the European references. The values from present study were found to be in the lower range of the European biometric values. Conclusion: Normal biometric MRI data of the foetal brain in an Indian population from 20 to 38 weeks gestational age was presented. A significant correlation was found between gestational age and parameters. MRI BPD and HC values showed a positive correlation with ultrasound BPD and HC values.https://www.jcdr.net/articles/PDF/16855/56573_CE(AnK)_F[SH]_PF1(SC_SS)_PFA(SC_SS)_PN(SS).pdfbiparietal diametergestational agehead circumferenceoccipital length |
| spellingShingle | Chandrasekhar Priyanka Rajeswaran Rangasami Chitra Andrew N Paarthipan Foetal Brain Biometry using Magnetic Resonance Imaging in an Indian Population- A Retrospective Cohort Study Journal of Clinical and Diagnostic Research biparietal diameter gestational age head circumference occipital length |
| title | Foetal Brain Biometry using Magnetic Resonance Imaging in an Indian Population- A Retrospective Cohort Study |
| title_full | Foetal Brain Biometry using Magnetic Resonance Imaging in an Indian Population- A Retrospective Cohort Study |
| title_fullStr | Foetal Brain Biometry using Magnetic Resonance Imaging in an Indian Population- A Retrospective Cohort Study |
| title_full_unstemmed | Foetal Brain Biometry using Magnetic Resonance Imaging in an Indian Population- A Retrospective Cohort Study |
| title_short | Foetal Brain Biometry using Magnetic Resonance Imaging in an Indian Population- A Retrospective Cohort Study |
| title_sort | foetal brain biometry using magnetic resonance imaging in an indian population a retrospective cohort study |
| topic | biparietal diameter gestational age head circumference occipital length |
| url | https://www.jcdr.net/articles/PDF/16855/56573_CE(AnK)_F[SH]_PF1(SC_SS)_PFA(SC_SS)_PN(SS).pdf |
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