Laparoscopic Vaginoplasty Procedure Using a Modified Peritoneal Pull-Down Technique with Uterine Strand Incision in Patients with Mayer–Rokitansky–Küster–Hauser Syndrome: Kisu Modification

Various vaginoplasty procedures have been developed for patients with Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome. Here, we describe a novel laparoscopic vaginoplasty procedure, known as the Kisu modification, using a pull-down technique of the peritoneal flaps with additional structural support...

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Main Authors: Iori Kisu, Miho Iida, Kanako Nakamura, Kouji Banno, Tetsuro Shiraishi, Asahi Tokuoka, Keigo Yamaguchi, Kunio Tanaka, Moito Iijima, Hiroshi Senba, Kiyoko Matsuda, Nobumaru Hirao
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/23/5510
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author Iori Kisu
Miho Iida
Kanako Nakamura
Kouji Banno
Tetsuro Shiraishi
Asahi Tokuoka
Keigo Yamaguchi
Kunio Tanaka
Moito Iijima
Hiroshi Senba
Kiyoko Matsuda
Nobumaru Hirao
author_facet Iori Kisu
Miho Iida
Kanako Nakamura
Kouji Banno
Tetsuro Shiraishi
Asahi Tokuoka
Keigo Yamaguchi
Kunio Tanaka
Moito Iijima
Hiroshi Senba
Kiyoko Matsuda
Nobumaru Hirao
author_sort Iori Kisu
collection DOAJ
description Various vaginoplasty procedures have been developed for patients with Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome. Here, we describe a novel laparoscopic vaginoplasty procedure, known as the Kisu modification, using a pull-down technique of the peritoneal flaps with additional structural support to the neovaginal apex using the incised uterine strand in patients with MRKH syndrome. Ten patients with MRKH syndrome (mean age at surgery: 23.9 ± 6.5 years, mean postoperative follow-up period: 17.3 ± 3.7 months) underwent construction of a neovagina via laparoscopic vaginoplasty. All surgeries were performed successfully without complications. The mean neovaginal length at discharge was 10.3 ± 0.5 cm. Anatomical success was achieved in all patients, as two fingers were easily introduced, the neovagina was epithelialized, and the mean neovaginal length was 10.1 ± 1.0 cm 1 year postoperatively. No obliteration, granulation tissue formation at the neovaginal apex, or neovaginal prolapse was recorded. Five of the 10 patients attempted sexual intercourse and all five patients were satisfied with the sexual activity, indicating functional success. Although the number of cases in this case series is few, our favorable experience suggests that the Kisu modification of laparoscopic vaginoplasty procedure is an effective, feasible, and safe approach for neovaginal creation in patients with MRKH syndrome.
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spelling doaj.art-af64b5f6564742788489c33ce9fb161f2023-11-23T02:35:11ZengMDPI AGJournal of Clinical Medicine2077-03832021-11-011023551010.3390/jcm10235510Laparoscopic Vaginoplasty Procedure Using a Modified Peritoneal Pull-Down Technique with Uterine Strand Incision in Patients with Mayer–Rokitansky–Küster–Hauser Syndrome: Kisu ModificationIori Kisu0Miho Iida1Kanako Nakamura2Kouji Banno3Tetsuro Shiraishi4Asahi Tokuoka5Keigo Yamaguchi6Kunio Tanaka7Moito Iijima8Hiroshi Senba9Kiyoko Matsuda10Nobumaru Hirao11Department of Obstetrics and Gynecology, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, Tokyo 1908531, JapanDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo 1608582, JapanDepartment of Obstetrics and Gynecology, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, Tokyo 1908531, JapanDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo 1608582, JapanDepartment of Obstetrics and Gynecology, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, Tokyo 1908531, JapanDepartment of Obstetrics and Gynecology, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, Tokyo 1908531, JapanDepartment of Obstetrics and Gynecology, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, Tokyo 1908531, JapanDepartment of Obstetrics and Gynecology, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, Tokyo 1908531, JapanDepartment of Obstetrics and Gynecology, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, Tokyo 1908531, JapanDepartment of Obstetrics and Gynecology, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, Tokyo 1908531, JapanDepartment of Obstetrics and Gynecology, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, Tokyo 1908531, JapanDepartment of Obstetrics and Gynecology, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, Tokyo 1908531, JapanVarious vaginoplasty procedures have been developed for patients with Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome. Here, we describe a novel laparoscopic vaginoplasty procedure, known as the Kisu modification, using a pull-down technique of the peritoneal flaps with additional structural support to the neovaginal apex using the incised uterine strand in patients with MRKH syndrome. Ten patients with MRKH syndrome (mean age at surgery: 23.9 ± 6.5 years, mean postoperative follow-up period: 17.3 ± 3.7 months) underwent construction of a neovagina via laparoscopic vaginoplasty. All surgeries were performed successfully without complications. The mean neovaginal length at discharge was 10.3 ± 0.5 cm. Anatomical success was achieved in all patients, as two fingers were easily introduced, the neovagina was epithelialized, and the mean neovaginal length was 10.1 ± 1.0 cm 1 year postoperatively. No obliteration, granulation tissue formation at the neovaginal apex, or neovaginal prolapse was recorded. Five of the 10 patients attempted sexual intercourse and all five patients were satisfied with the sexual activity, indicating functional success. Although the number of cases in this case series is few, our favorable experience suggests that the Kisu modification of laparoscopic vaginoplasty procedure is an effective, feasible, and safe approach for neovaginal creation in patients with MRKH syndrome.https://www.mdpi.com/2077-0383/10/23/5510Davydov procedureMayer–Rokitansky–Küster–Hauser syndromeneovaginauterine factor infertilityuterus transplantationvaginoplasty
spellingShingle Iori Kisu
Miho Iida
Kanako Nakamura
Kouji Banno
Tetsuro Shiraishi
Asahi Tokuoka
Keigo Yamaguchi
Kunio Tanaka
Moito Iijima
Hiroshi Senba
Kiyoko Matsuda
Nobumaru Hirao
Laparoscopic Vaginoplasty Procedure Using a Modified Peritoneal Pull-Down Technique with Uterine Strand Incision in Patients with Mayer–Rokitansky–Küster–Hauser Syndrome: Kisu Modification
Journal of Clinical Medicine
Davydov procedure
Mayer–Rokitansky–Küster–Hauser syndrome
neovagina
uterine factor infertility
uterus transplantation
vaginoplasty
title Laparoscopic Vaginoplasty Procedure Using a Modified Peritoneal Pull-Down Technique with Uterine Strand Incision in Patients with Mayer–Rokitansky–Küster–Hauser Syndrome: Kisu Modification
title_full Laparoscopic Vaginoplasty Procedure Using a Modified Peritoneal Pull-Down Technique with Uterine Strand Incision in Patients with Mayer–Rokitansky–Küster–Hauser Syndrome: Kisu Modification
title_fullStr Laparoscopic Vaginoplasty Procedure Using a Modified Peritoneal Pull-Down Technique with Uterine Strand Incision in Patients with Mayer–Rokitansky–Küster–Hauser Syndrome: Kisu Modification
title_full_unstemmed Laparoscopic Vaginoplasty Procedure Using a Modified Peritoneal Pull-Down Technique with Uterine Strand Incision in Patients with Mayer–Rokitansky–Küster–Hauser Syndrome: Kisu Modification
title_short Laparoscopic Vaginoplasty Procedure Using a Modified Peritoneal Pull-Down Technique with Uterine Strand Incision in Patients with Mayer–Rokitansky–Küster–Hauser Syndrome: Kisu Modification
title_sort laparoscopic vaginoplasty procedure using a modified peritoneal pull down technique with uterine strand incision in patients with mayer rokitansky kuster hauser syndrome kisu modification
topic Davydov procedure
Mayer–Rokitansky–Küster–Hauser syndrome
neovagina
uterine factor infertility
uterus transplantation
vaginoplasty
url https://www.mdpi.com/2077-0383/10/23/5510
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