Secretion of pro‐angiogenic extracellular vesicles during hypoxia is dependent on the autophagy‐related protein GABARAPL1

Secretion of pro‐angiogenic extracellular vesicles during hypoxia is dependent on the autophagy‐related protein GABARAPL1

Abstract Tumour hypoxia is a hallmark of solid tumours and contributes to tumour progression, metastasis development and therapy resistance. In response to hypoxia, tumour cells secrete pro‐angiogenic factors to induce blood vessel formation and restore oxygen supply to hypoxic regions. Extracellula...

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Bibliografische gegevens
Hoofdauteurs:	Tom G. Keulers, Sten F. Libregts, Joel E.J. Beaumont, Kim G. Savelkouls, Johan Bussink, Hans Duimel, Ludwig Dubois, Marijke I. Zonneveld, Carmen López‐Iglesias, Karel Bezstarosti, Jeroen A. Demmers, Marc Vooijs, Marca Wauben, Kasper M.A. Rouschop
Formaat:	Artikel
Taal:	English
Gepubliceerd in:	Wiley 2021-12-01
Reeks:	Journal of Extracellular Vesicles
Onderwerpen:	autophagy exosomes extracellular vesicles GABARAPL1 hypoxia
Online toegang:	https://doi.org/10.1002/jev2.12166

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